Results 91 to 100 of about 1,514,462 (352)

Trajectories of self-rated health in people with diabetes: Associations with functioning in a prospective community sample [PDF]

, 2013
© 2013 Schmitz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Sacker, A Sacker, A Zajacova, Alain Lesage, Ashok Malla, B Han, BG Fincke, BL Jones, BL Jones, CH Hennessy, EJ Ludman, EL Idler, EL Idler, F Lamers, G Andrews, Geneviève Gariépy, H Andruff, Hamid Reza Baradaran, HL Lee, Irene Strychar, J Banks, J Liang, JA Salomon, JB Dowd, JianLi Wang, , K Kroenke, KA Sargent-Cox, Kimberley J. Smith, LA Chwastiak, M Jylha, N Schmitz, NO Månsson, Norbert Schmitz, O Garin, O Pietilainen, P Ayyagari, P Diehr, PGN Kramers, PM Fayers, RE Foraker, Richard Boyer, S Gilbody, S Moussavi, W Katon, Y Benyamini   +44 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Proposed Standards for Variable Harmonization Documentation and Referencing: A Case Study Using QuickCharmStats 1.1. [PDF]

PLoS ONE, 2016
Comparative statistical analyses often require data harmonization, yet the social sciences do not have clear operationalization frameworks that guide and homogenize variable coding decisions across disciplines.
Kristi Winters, Sebastian Netscher
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The experiences of medical and pharmacy students participating in a collaborative online international learning on social accountability and global health: a qualitative study

BMC Medical Education
Background Social accountability aims to promote a collective ethic that upholds the fundamental values of equity, efficiency, solidarity, and social justice in healthcare and is now considered as a critical mission of academic health centers ...
Anne-Emmanuelle Rault, Janie Giard, Joël Ladner, Offoue Kra, Raphaël Randrianarivo, Marceau Chenault, Edouard Leaune   +6 more
doaj   +1 more source

Transfer Topic Labeling with Domain-Specific Knowledge Base: An Analysis of UK House of Commons Speeches 1935-2014 [PDF]

, 2018
Topic models are widely used in natural language processing, allowing researchers to estimate the underlying themes in a collection of documents. Most topic models use unsupervised methods and hence require the additional step of attaching meaningful ...
Herzog, Alexander, John, Peter, Mikhaylov, Slava Jankin   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Neurocognitive Process of Digital Radicalization: A Theoretical Model and Analytical Framework [PDF]

, 2019
Recent studies suggest that empathy induced by narrative messages can effectively facilitate persuasion and reduce psychological reactance. Although limited, emerging research on the etiology of radical political behavior has begun to explore the role of
Benning, Stephen D., Howard, Tiffiany, Poston, Brach   +2 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Characteristics of outdoor falls among older people: A qualitative study [PDF]

, 2013
Background Falls are a major threat to older people’s health and wellbeing. Approximately half of falls occur in outdoor environments but little is known about the circumstances in which they occur.
A Bergland, A Nathan, A Shumway-Cook, A Shumway-Cook, A Ståhl, AC King, AH Ranhoff, AL Rosso, AR Eisenstein, AR Levy, C Beynon, C Robson, C Willig, CJ Cherpitel, Claire Ballinger, DC Landy, DE Rosenberg, DL Morgan, E Stack, F Bunn, GJ Wijlhuizen, GJ Wijlhuizen, H-W Wahl, HM Hanson, J Fleming, J Kerr, J Phillips, J Ritchie, J Ritchie, JL Kelsey, JL Kelsey, JL Kelsey, Judith E Phillips, K Horton, K Sjogren, KR Fox, L Asher, L Clemson, L Clemson, L Gauvin, L Salonen, L Yardley, L Yardley, LA Talbot, LD Gillespie, M Annear, M Rantakokko, M Rantakokko, M Rantakokko, M Rantakokko, MC Nevitt, MG Davis, MHC Bleijlevens, MRU Meyer, N Owen, NM Peel, O Beauchet, P Morency, PA Bath, Panel on Prevention of Falls in Older Persons, American Geriatrics Society, British Geriatrics Society, PC Lai, PC Lai, R Newton, Rita Newton, S Turner, S Wilkinson, Samuel R Nyman, SC Webber, SE Lamb, SR Cummings, SR Lord, SR Lord, TE Finnes, W Li, World Health Organization, Y Rydin, YH Chu, YL Michael   +77 more
core   +2 more sources