Results 111 to 120 of about 1,449,532 (381)

Automatic Detection of Everyday Social Behaviours and Environments from Verbatim Transcripts of Daily Conversations

Annual IEEE International Conference on Pervasive Computing and Communications, 2019
Coding in social sciences is a process that involves the categorisation of qualitative or quantitative data in order to facilitate further analysis. Coding is usually a manual process that involves a lot of effort and time to produce codes with high ...
Kristina Yordanova, Burcu Demiray, M. Mehl, Mike Martin   +3 more
semanticscholar   +1 more source

The impact of patients' chronic disease on family quality of life : an experience from 26 specialties [PDF]

, 2013
BACKGROUND: Previous studies have assessed family quality of life in individual disease areas and specialties. The aim of this study was to investigate the impact of disease on family members of patients over a wide range of specialties and identify key ...
Basra, Mohammad Khurshid Azam, Finlay, Andrew Yule, Golics, Catherine Jane, Salek, M Sam   +3 more
core   +3 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Trajectories of self-rated health in people with diabetes: Associations with functioning in a prospective community sample [PDF]

, 2013
© 2013 Schmitz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Sacker, A Sacker, A Zajacova, Alain Lesage, Ashok Malla, B Han, BG Fincke, BL Jones, BL Jones, CH Hennessy, EJ Ludman, EL Idler, EL Idler, F Lamers, G Andrews, Geneviève Gariépy, H Andruff, Hamid Reza Baradaran, HL Lee, Irene Strychar, J Banks, J Liang, JA Salomon, JB Dowd, JianLi Wang, , K Kroenke, KA Sargent-Cox, Kimberley J. Smith, LA Chwastiak, M Jylha, N Schmitz, NO Månsson, Norbert Schmitz, O Garin, O Pietilainen, P Ayyagari, P Diehr, PGN Kramers, PM Fayers, RE Foraker, Richard Boyer, S Gilbody, S Moussavi, W Katon, Y Benyamini   +44 more
core   +2 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

The experiences of medical and pharmacy students participating in a collaborative online international learning on social accountability and global health: a qualitative study

BMC Medical Education
Background Social accountability aims to promote a collective ethic that upholds the fundamental values of equity, efficiency, solidarity, and social justice in healthcare and is now considered as a critical mission of academic health centers ...
Anne-Emmanuelle Rault, Janie Giard, Joël Ladner, Offoue Kra, Raphaël Randrianarivo, Marceau Chenault, Edouard Leaune   +6 more
doaj   +1 more source

Unmasking Machine Learning With Tensor Decomposition: An Illustrative Example for Media and Communication Researchers

Media and Communication
As online communication data continues to grow, manual content analysis, which is frequently employed in media studies within the social sciences, faces challenges in terms of scalability, efficiency, and coding scope.
Yu Won Oh, Chong Hyun Park
doaj   +1 more source

Connecting key competencies and social inquiry in primary social studies pedagogy: initial teacher education students' planning decisions and reflections. [PDF]

, 2010
Over 2007-2009 we have worked with the national curriculum's key competencies to establish their place and purpose in the social sciences learning area.
Hunter, Philippa Anne, Keown, Paul Ashley, Wynyard, Jill   +2 more
core   +2 more sources

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source