Results 121 to 130 of about 1,514,462 (352)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
GROUNDED THEORY AND SOCIAL-PEDAGOGICAL RESEARCH
Debates on the application of the quantitative, qualitative or mixed methodological approaches in social sciences are mainly driven by the need to justify meaning and scope of qualitative research in the context of modern science. In this sense, the aim
Olivera Č. Knežević-Florić +1 more
doaj
Barriers to Research in the Humanities in Iran: a window to Science Policy
Conducting research in humanities sciences in Iran is faces with different barriers, including the small number of researchers, financial resources shortage, weak research infrastructure, etc.
Behrooz Rasuli, Parviz Shahriari
doaj
The Role of Imagination in Social Scientific Discovery: Why Machine Discoverers Will Need Imagination Algorithms [PDF]
When philosophers discuss the possibility of machines making scientific discoveries, they typically focus on discoveries in physics, biology, chemistry and mathematics.
Stuart, Michael
core
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Presentation of organizational culture model of elementary schools of alborz province
Background: Organizational culture plays a role in human behavior and is one of the most important concepts in behavioral sciences. But so far it has not been fully evaluated.
Maryam sasanian +4 more
doaj
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Promoting Novelty, Rigor, and Style in Energy Social Science: Towards Codes of Practice for Appropriate Methods and Research Design [PDF]
Benjamin K. Sovacool +2 more
openalex +3 more sources
A Meta-Analysis of Procedures to Change Implicit Measures [PDF]
Using a novel technique known as network meta-analysis, we synthesized evidence from 492 studies (87,418 participants) to investigate the effectiveness of procedures in changing implicit measures, which we define as response biases on implicit tasks.
Ast, Jordan R. +6 more
core +2 more sources

