Results 141 to 150 of about 741,973 (309)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Role of Imagination in Social Scientific Discovery: Why Machine Discoverers Will Need Imagination Algorithms [PDF]
, 2019 When philosophers discuss the possibility of machines making scientific discoveries, they typically focus on discoveries in physics, biology, chemistry and mathematics.
Stuart, Michael
core
Emerging strategies to target metastasis and therapy resistance in melanoma
Molecular Oncology, EarlyView.Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley +1 more source
Investigating the Challenges of Infertility Treatment Development in Centers of Iran University of Medical Sciences and Health Services [PDF]
Journal of Evidence Based Health Policy, Management & EconomicsBackground: The desire for the survival of the generation, although it is a non-physical need, cannot be achieved without physical health. With the reduction of the country's population growth to less than one percent, the concern about the future of the
Fatemeh Najafi Pourmoghadam +6 more
doaj
A framework for the adoption and diffusion of Personal Learning Environments in commercial organisations: an exploratory study in the learning and development sector in the UK [PDF]
, 2011 This study presents an exploratory approach to identify the main factors of Personal Learning Environment (PLE) adoption and diffusion within commercial organisations.
Chatterjee, Arunangsu +4 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2023 Common Principles and Code of Conduct for the Application of SS4CE in HA is a partnership with SoNAR-Global, Makerere University of Uganda, Fundación Osvaldo Cruz and members of Technical Working Group-1 (TWG-1) . These recommended principles are the outcome of two previous deliverables produced by the project; the ethics and data sharing mapping and ...
Matta, Gustavo +8 more
openaire +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source