Results 141 to 150 of about 1,765,355 (377)
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Digitally-aided reviews of large bodies of text-based information, such as academic literature, are growing in capability but are not yet common in environmental fields.
Emily Grubert, Anne Siders
doaj +1 more source
Social Sciences for Community Engagement in Humanitarian Action - Codes of Conduct Mapping
The mapping of codes of conduct (CoC) for the application of SS4CE in HA is a partnership with Sonar-Global, Makerere University of Uganda and members of Technical Working Group-1 (TWG-1). This assessment was envisioned to review existing codes of conduct currently applied in the humanitarian system and academic world, related to social sciences and ...
Kawa Mafigiri, David+6 more
openaire +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Of impacts, agents, and functions: An interdisciplinary meta-review of smart home energy management systems research [PDF]
Smart home energy management technologies (SHEMS) have long been viewed as a promising opportunity to manage the way households use energy. Research on this topic has emerged across a variety of disciplines, focusing on different pieces of the SHEMS ...
McIlvennie, C+2 more
core
LEAP: LLM-powered End-to-end Automatic Library for Processing Social Science Queries on Unstructured Data [PDF]
Social scientists are increasingly interested in analyzing the semantic information (e.g., emotion) of unstructured data (e.g., Tweets), where the semantic information is not natively present. Performing this analysis in a cost-efficient manner requires using machine learning (ML) models to extract the semantic information and subsequently analyze the ...
arxiv +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
GROUNDED THEORY AND SOCIAL-PEDAGOGICAL RESEARCH
Debates on the application of the quantitative, qualitative or mixed methodological approaches in social sciences are mainly driven by the need to justify meaning and scope of qualitative research in the context of modern science. In this sense, the aim
Olivera Č. Knežević-Florić+1 more
doaj
Barriers to Research in the Humanities in Iran: a window to Science Policy
Conducting research in humanities sciences in Iran is faces with different barriers, including the small number of researchers, financial resources shortage, weak research infrastructure, etc.
Behrooz Rasuli, Parviz Shahriari
doaj