Results 151 to 160 of about 1,449,532 (381)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Relationship between social and cognitive functions in people with schizophrenia

Neuropsychiatric Disease and Treatment, 2018
Takeo Tominaga,1 Masahito Tomotake,2 Tomoya Takeda,1 Yoshinori Ueoka,3 Tsunehiko Tanaka,4 Shin-ya Watanabe,1 Naomi Kameoka,5 Masahito Nakataki,5 Shusuke Numata,1 Yumiko Izaki,6 Satsuki Sumitani,7 Hiroko Kubo,8 Yasuhiro Kaneda,9 Tetsuro Ohmori1 ...
Tominaga T, Tomotake M, Takeda T, Ueoka Y, Tanaka T, Watanabe SY, Kameoka N, Nakataki M, Numata S, Izaki Y, Sumitani S, Kubo H, Kaneda Y, Ohmori T   +13 more
doaj  

Presentation of organizational culture model of elementary schools of alborz province

مجله علوم روانشناختی, 2020
Background: Organizational culture plays a role in human behavior and is one of the most important concepts in behavioral sciences. But so far it has not been fully evaluated.
Maryam sasanian, Abbas Khorshidi, Fatemeh hamidifar, Asghar moshabbaki, Alireza araghieh   +4 more
doaj  

Towards efficient and reliable utilization of automated data collection: Media scrapers applied to news on climate change [PDF]

Journal of Data Mining and Digital Humanities
: Automated data collection provides tempting opportunities for social sciences and humanities studies. Abundant data accumulating in various digital archives allows more comprehensive, timely and cost-efficient ways of harvesting and processing ...
Erkki Mervaala, Jari Lyytimäki
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

The Convergence of Prompt-Based Coding and No-Code/Low-Code Tools: Implications for Software Development and Social Sciences

This book compiles a collection of seminal and contemporary research exploring the burgeoning intersection of large language models (LLMs) and various disciplines, alongside the evolving field of prompt engineering. The included works collectively illuminate the transformative potential of these technologies, while also critically examining their ...
openaire   +8 more sources

Journal of Siberian Federal University. Humanities & Social Sciences [PDF]

Journal of Siberian Federal University. Humanities & Social Sciences, 2018
Ни одна другая часть земного шара не сталкивается с такими значительными климатическими изменениями, как Арктика. С течением времени становится невозможным продолжать традиционный образ жизни. Все живущие и работающие в этом регионе вынуждены адаптироваться к стремительно меняющейся реальности.
openaire   +4 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Social Sciences for Community Engagement in Humanitarian Action (SS4CE in HA) - Common Principles and Code of Conduct for the Application of SS4CE in HA

, 2023
Common Principles and Code of Conduct for the Application of SS4CE in HA is a partnership with SoNAR-Global, Makerere University of Uganda, Fundación Osvaldo Cruz and members of Technical Working Group-1 (TWG-1) . These recommended principles are the outcome of two previous deliverables produced by the project; the ethics and data sharing mapping and ...
Matta, Gustavo, Cortez-Gómez, Renata, Degrave, Aline, Kawa Mafigiri, David, Ekusai, Deborah, Constance, Iradukunda, Lana, Benedetta, Falero Cusano, Maria Fernanda, Elessawi, Rania   +8 more
openaire   +1 more source