Results 51 to 60 of about 929,664 (308)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Data on perceived excessive workload on faculty members׳ commitment

Data in Brief, 2018
For this article, the survey data on the effect of perceived excessive workload on faculty members’ commitment was presented. This data was gathered from an academic environment using the full time faculty members of Covenant University.
Olumuyiwa A. Oludayo, Comfort O. Akanbi, Hezekiah O. Falola, Oluwafisayo A. Aluko   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Intersectional Invisibility in Women’s Diversity Interventions

Frontiers in Psychology, 2022
Many diversity interventions for women are ineffective. One reason for this may be that the field that diversity interventions are usually based on, the social sciences, often do not consider intra-group differences among women. Specifically, differences
Chuk Yan E. Wong, Teri A. Kirby, Teri A. Kirby, Floor Rink, Michelle K. Ryan, Michelle K. Ryan, Michelle K. Ryan   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The Phenomenon of Bullying in Schools as a Basis for Developing Social Studies Learning Materials

Qalamuna
This qualitative research aims to analyze the phenomenon of bullying in schools to develop social sciences learning materials using literature studies and thematic synthesis.
Ares Faujian, Anik Widiastuti, Sudrajat Sudrajat   +2 more
doaj   +1 more source

Teaching History in vulnerable high schools in Araucanía, Chile: a qualitative research

Ricerche di Pedagogia e Didattica, 2013
Nowadays, History and Social Sciences teaching in high school level is oriented from a training based in competencies to generate different levels of achievement and learning outcomes.
Juan Mansilla Sepúlveda, Claudia Andrea Huaiquián Billeke   +1 more
doaj   +1 more source

Understanding the Lived Experiences of People Sleeping Rough in Tehran [PDF]

پژوهشنامه مددکاری اجتماعی, 2017
Understanding the Lived Experiences of People Sleeping Rough in Tehran Akbar Bakhshinia[1]  ,  Habib Aghabakhshi[2]  ,  Saeed Zokaei[3]  Received: 3/10/2018               Accepted: 27/1/2019   Abstract   In the recent two decades, a special kind of ...
Akbar Bakhshi nia, h a, m z
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A workplace well-being game intervention for health sciences librarians to address burnout

Journal of the Medical Library Association, 2020
Objective: The authors measured burnout among health sciences librarians at our institution and determined whether a serious game intervention could improve personal and workplace well-being.
Tallie Casucci, Amy B. Locke, Autumn Henson, Fares Qeadan   +3 more
doaj   +1 more source