Results 131 to 140 of about 445,931 (266)

Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

, 2014
We present a comprehensive analysis of stop codon usage in bacteria by analyzing over eight million coding sequences of 4684 bacterial sequences. Using a newly developed program called "stop codon counter," the frequencies of the three classical stop ...
Holm, Mikael,, Sanyal, Suparna,, Korkmaz, Gürkan,, Wiens, Tobias,   +3 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Improvements in codon usage analysis for a more detailed understanding of genome content and horizontal gene transfer [PDF]

, 2010
The genetic code has evolved with considerable elasticity, enabling most amino acids to be encoded by multiple synonymous codons. Genes can vary in their utilization of synonymous codons, and this provides a basis of comparison for studying the ...
Davis, James J.
core  

Codon-optimized glucoamylase sGAI of Aspergillus awamori improves starch utilization in an industrial yeast

, 2012
ArticleThe development of a yeast that converts raw starch to ethanol in one step (called consolidated bioprocessing) could yield large cost reductions in the bioethanol industry. The aim of this study was to develop an efficient amylolytic Saccharomyces
Saayman M., Casella S., Favaro L., Van Zyl W.H., Jooste T., Basaglia M., Gorgens J.F., Rose S.H.   +7 more
core   +1 more source

Clinicopathological features and outcomes for colorectal carcinomas with KRAS codon 146 mutations

ESMO Gastrointestinal Oncology
Background: KRAS-activating mutations characterize ∼40% of colorectal carcinomas (CRCs) and predict resistance to anti-epidermal growth factor receptor therapy.
R.K. Yang, A. Rashid, S. Roy-Chowdhuri, D.S. Hong, J. Bryan   +4 more
doaj   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Retraction Announcement [PDF]

N/
Codon Publications
core   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Source code release for: Gaussian distributed codon frequencies of genomes

, 2019
<p>Source code to accompany the publication:</p> <p>Khomtchouk BB, Nonner W: "Gaussian-distributed codon frequencies of genomes", <em>G3 (Bethesda)</em>, 2019 (in press).</p ...
Bohdan Khomtchouk, Wolfgang Nonner
core   +1 more source

SiDT1 Defines Plant Architecture Reminiscent of Green Revolution in Foxtail Millet

Advanced Science, EarlyView.
SiDT1 encodes a GA3‐oxidase that creates a semi‐dwarf, lodging‐resistant architecture reminiscent of the rice Green Revolution. The resulting ideotype performs well under dense planting and provides a valuable genetic resource for high‐yield, mechanized foxtail millet production. ABSTRACT Foxtail millet (Setaria italica) is a drought‐tolerant C4 cereal
Jianzhen Lv, Jinjin Cheng, Zhen Hu, Qian Lan, Yanjun Yang, Chengcheng Pei, Junhao Luo, Zhuang Li, Peiyong Xin, Jijun Yan, Jinfang Chu, Qian Qian, Zhaosheng Kong, Liang Jiang   +13 more
wiley   +1 more source