Results 111 to 120 of about 445,931 (266)
Codon-triplet context unveils unique features of the protein coding genome-4
, 2011 Copyright information:Taken from "Codon-triplet context unveils unique features of the protein coding genome"http://www.biomedcentral.com/1471-2164/8/444BMC Genomics 2007;8():444-444.Published online 29 Nov 2007PMCID:PMC2244636.have computed separated ...
Laura Carreto (34863) +6 more
core +1 more source
Phylogenetic Analysis and Codon Usage Bias of Chloroplast Genomes in Rhododendron
Guangdong nongye kexue【Objective】The objective of this study was to analyze the codon usage patterns in the chloroplast genome of Rhododendron, aiming to provide genetic information for the conservation and innovation of Rhododendron germplasm resources and to lay a ...
Yulei MA +4 more
doaj +1 more source
BMC Research Notes, 2012 Background Synonymous codon usage bias has typically been correlated with, and attributed to translational efficiency. However, there are other pressures on genomic sequence composition that can affect codon usage patterns such as mutational biases. This
O'Connell Mary J +6 more
doaj +1 more source
Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos +5 more
wiley +1 more source
Differences in codon usage between host-species-specific rabies virus clades are driven by non-GC3 nucleotide composition [PDF]
Viral genes sometimes use certain codons more than others due to their nucleotide content, translational efficiency, and selection pressure from the host immune system. The rabies virus (RABV) is a negative strand RNA virus which can infect a broad range
Dushoff, Jonathan +4 more
core +1 more source
Evolutionary pressures on the yeast transcriptome [PDF]
, 2015 Codon usage bias (CUB) is the well known phenomenon that the frequency of synonymous codons is unequal. This is presumably the result of adaptive pressures favouring some codons over others.
Chu, Dominique, Salykin, Anton
core +1 more source
BMC Evolutionary Biology, 2011 Background Accurate modelling of substitution processes in protein-coding sequences is often hampered by the computational burdens associated with full codon models. Lately, codon partition models have been proposed as a viable alternative, mimicking the
Baele Guy +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Dataset of 313 metagenome-assemble genomes from streamer hot spring water
Data in BriefThis data report presents prokaryotic metagenome-assembled genomes (MAGs) from a hot spring stream with temperatures between 64 and 100°C. The stream water was filtered and the extracted total DNA was sequenced using the Illumina HiSeq 2500 platform ...
Jia Hao Tan, Kok Jun Liew, Kian Mau Goh
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source