Results 81 to 90 of about 370,078 (259)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Usos del coeficiente alfa de Cronbach en el análisis de instrumentos escritos
Revista Médica ElectrónicaSe realizó un estudio de carácter evaluativo para determinar la precisión de un examen escrito mediante un análisis de fiabilidad. El examen, integrado por 30 preguntas que exploran cierto tipo de conocimiento profesional, se aplicó a 45 personas, y con ...
Silvio Faustino Soler Cárdenas +1 more
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Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
The Role of Item Distributions on Reliability Estimation: The Case of Cronbach's Coefficient Alpha. [PDF]
Educ Psychol Meas, 2020 Olvera Astivia OL, Kroc E, Zumbo BD.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
On the use of coefficient alpha in multidimensional scales: a reanalysis Pena-Rodriguez, et al
Revista Habanera de Ciencias Médicas, 2016 Carta al editor que resalta las condiciones en las cuales debe ser usado el coeficiente alfa de Cronbach.
Sergio Alexis Dominguez Lara
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Huli yanjiu, 2018 To evaluate the applicability of impact on participation and autonomy questionnaire(IPA) in schizophrenic patients in China.Methods:A total of 185 patients with schizophrenia and conforming to the inclusion criteria were selected by IPA using the ...
孔庆芳, 施忠英, 盛梅青, 高麒
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