Results 91 to 100 of about 174,135,443 (297)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Coefficient of variation of the three biomarkers of fibrosis.

, 2018
Coefficient of variation of the three biomarkers of fibrosis.
Andrea Dennis (5728271), Martine M. Fiore (5728274), Stefan Neubauer (88474), Peter G. Traber (468972), Rajarshi Banerjee (2290225), Stephen A. Harrison (393367), Angelo H. Paredes (5728280), Matt D. Kelly (5728277), Catherine J. Kelly (775254), Jennifer M. Whitehead (5728283)   +9 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Coefficient of variation of the STA-PSV detection.

, 2012
Coefficient of variation of the STA-PSV detection.
Yao Wang (102387), Xiaolong Zhao (119086), Ling Li (38566), Fangfang Zeng (119108), Linuo Zhou (119102), Yiming Li (40290), Hong Liu (50694), Renming Hu (107418), Lili Chen (66681), Yong Wang (12837)   +9 more
core   +1 more source

Manuscript - Coefficient of variation in wheat

, 2021
Supporting material for "Bayesian and Frequentist meta-analysis reveals the distribution of coefficient of variation over a half-century of wheat experiments published in ...
Maicon Nardino, Tiago Olivoto
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Variation curve of permeability coefficient of coal seam.

, 2018
Variation curve of permeability coefficient of coal seam.
Jin Pan (411619), Feng Zhang (6548), Zheng Shang (5465090), Zhengyi Ti (5465093), Xiaofei Ma (552408)   +4 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Characterisation of sweet stem sorghum genotypes for bio-ethanol production

Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2018
In an effort to characterise and select promising sweet stem sorghum genotypes with enhanced biofuel productivity, the present study investigated phenotypic variability present among diverse sweet stem sorghum genotypes based on ethanol production and ...
Precious Mangena, Hussein Shimelis, Mark Laing   +2 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source