Results 71 to 80 of about 2,378,304 (340)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Analysis of Vertical Heterogeneity Measures Based on Routine Core Data of Sandstone Reservoirs
GeosciencesHeterogeneous reservoirs are prevalent; otherwise, they are rare. The problem is detecting the degree of such heterogeneity, which has a significant impact on hydrocarbon production in oilfields. Several vertical heterogeneity measures were introduced to
Mohamed S. El Sharawy
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Evaluation of hydraulic characteristics of several types of drip irrigation tapes
علوم آب و خاک, 2017 The main purpose of this study is investigation of hydraulic properties in drip irrigation tape. In this study, 10 types of drip irrigation tape were tested, and the effect of 4 temperatures of water, 13, 23, 33 and 43 °C, was investigated according to ...
F. Gavazi, E. Maroufpoor
doaj
Coefficient of variation and Power Pen's parade computation [PDF]
Under the the assumption that income y is a power function of its rank among n individuals, we approximate the coefficient of variation and gini index as functions of the power degree of the Pen's parade.
Jules Sadefo Kamdem
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Effect of concentration dependence of the diffusion coefficient on homogenization kinetics in multiphase binary alloy systems [PDF]
Diffusion calculations were performed to establish the conditions under which concentration dependence of the diffusion coefficient was important in single, two, and three phase binary alloy systems.
Tenney, D. R., Unnam, J.
core +1 more source
Testing for a constant coefficient of variation in nonparametric regression [PDF]
, 2007 In this paper we propose a new test for the hypothesis of a constant coefficient of variation in the common nonparametric regression model. The test is based on an estimate of the $L^2$-distance between the square of the regression function and variance ...
Gabriele Wieczorek +3 more
core +1 more source
, 2013 Thermal variation of structural property, linear thermal expansion coefficient, resistivity, thermopower and power factor of polycrystalline Bi1-xSbx (x=0.10, 0.14) samples are reported.
Bandyopadhyay, S. +6 more
core +1 more source