Results 41 to 50 of about 353,415 (304)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

In spite of difference : making sense of the coexistence between the Kamba and the Maasai peoples of Kenya [PDF]

, 2003
Mutie PM. In spite of difference : making sense of the coexistence between the Kamba and the Maasai peoples of Kenya. Bielefeld (Germany): Bielefeld University; 2003.The study seeks to deepen understanding on "interethnic coexistence".
Mutie, Pius Mutuku
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

School Coexistence Problems in Students after the Confinement due to the SARS Pandemic COVID -19 in two Educational Institutions [PDF]

, 2023
La presente investigación tiene como propósito establecer las características que influyen en la convivencia escolar de estudiantes en dos instituciones de educación básica, para esto se hizo un caso de estudio que nos permitió determinar las ...
Morales Quintero, Diana Milena, Cortez Banqueth, Luz Adriana   +1 more
core  

Applying Forecasting Algorithms to Improve Budget Preparation Procedures in Government Units

تنمیة الرافدین
It is necessary to use contemporary techniques to anticipate government budget items in light of the financial difficulties that governments face, especially scarce resources and growing spending demands.
Doaa Adreese Younis
doaj   +1 more source

Intra-guild spatial niche overlap among three small falcon species in an area of recent sympatry

The European Zoological Journal, 2022
Climate warming and land-use change are reshuffling the distribution of wild organisms on a global scale. Some species may expand their ranges and colonize new regions, which may greatly affect ecological interactions among pre-existing species and ...
A. Berlusconi, D. Preatoni, G. Assandri, F. Bisi, M. Brambilla, J. G. Cecere, S. Cioccarelli, N. Grattini, M. Gustin, A. Martinoli, D. Rubolini, A. Sbrilli, A. Zanichelli, A. Martinoli, M. Morganti   +14 more
doaj   +1 more source

Coexistence of Pregnancy and Malignancy [PDF]

The Oncologist, 2002
Abstract Cancer complicating pregnancy is a rare coexistence. The incidence is approximately 1 in 1,000 pregnancies. The most common cancers are those more frequently seen during the reproductive age of a woman. Breast cancer, cervical cancer, Hodgkin's disease, malignant melanoma, and leukemias are the most frequently diagnosed ...
openaire   +4 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Theory of microbial coexistence in promoting soil–plant ecosystem health

, 2021
International audienceA healthy soil plant continuum is critical for maintaining agroecosystem functions and ensuring food security, which is thebasis of sustainable agricultural development.
Nunan, N., Sun, B., Sun, Bo, Zhou, Jizhong, Hirsch, P. R., Hirsch, Penny, Liang, Yuting, Zhang, Na, Nunan, Naoise, Zhang, N., Liang, Y., Zhou, J.   +11 more
core   +1 more source