Results 61 to 70 of about 287,585 (313)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

“Leave it to the experts”: Misleading narratives drive public voting on a wildlife protection ballot initiative

Conservation Science and Practice
As public values toward wildlife shift, some stakeholders are turning towards ballot initiatives to promote their values in management decision making.
Rebecca M. Niemiec, Mireille Gonzalez, Jenna Brager, Lori Kogan   +3 more
doaj   +1 more source

Biologically Inspired Self-Stabilizing Control for Bipedal Robots

International Journal of Advanced Robotic Systems, 2013
Despite recent major advances in computational power and control algorithms, the stable and robust control of a bipedal robot is still a challenging issue due to the complexity and high nonlinearity of robot dynamics.
Woosung Yang, Hyungjoo Kim, Bum Jae You
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

School Coexistence Problems in Students after the Confinement due to the SARS Pandemic COVID -19 in two Educational Institutions

, 2023
La presente investigación tiene como propósito establecer las características que influyen en la convivencia escolar de estudiantes en dos instituciones de educación básica, para esto se hizo un caso de estudio que nos permitió determinar las ...
Morales Quintero, Diana Milena, Cortez Banqueth, Luz Adriana   +1 more
core  

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Species-specific traits plus stabilizing processes best explain coexistence in biodiverse fire-prone plant communities

, 2013
Coexistence in fire-prone Mediterranean-type shrublands has been explored in the past using both neutral and niche-based models. However, distinct differences between plant functional types (PFTs), such as fire-killed vs resprouting responses to fire ...
Reineking Björn, Enright, N.J., Jürgen Groeneveld, Enright, Neal, Björn Reineking (113977), Byron B Lamont, Lamont, Byron, Reineking, B., Frank, K., Byron B. Lamont (296799), George L W Perry, Reineking, Bjorn, Neal J. Enright (296801), Karin Frank (211485), Groeneveld, Jurgen, Neal J Enright, Lamont Byron B., Jürgen Groeneveld (416288), George L. W. Perry (416289), Frank Karin, Groeneveld Jürgen, Perry, G.L.W., Perry, George, Lamont, B.B., Perry George L. W., Björn Reineking, Karin Frank, Perry, G., Enright Neal J., Groeneveld, J., Frank, Karin   +30 more
core   +1 more source

Metaverse as a concept involving the coexistence of many virtual 3D worlds

, 2023
The article presents interesting new concept called Metaverse as a concept involving the coexistence of many virtual 3D worlds. The first part presents definition and history of the concept and moving forward some challenges related to MV.
Norbert Kawęcki
core   +1 more source

Shopping Centers as Elements of the Functional and Spatial Structures of Cities. Location, Impact, Change Tendencies, Development Perspectives

Barometr Regionalny, 2017
The appearance of large-surface complexes has led to the creation of new trade, service and entertainment centers in cities; these complexes have an impact on their surroundings. Due to the large scale of the phenomenon, it is important to determine the
Agnieszka Rochmińska
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source