Results 121 to 130 of about 418,378 (371)

A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription

The EMBO Journal, 2003
Transcriptional activation from chromatin by nuclear receptors (NRs) requires multiple cofactors including CBP/p300, SWI/SNF and Mediator. How NRs recruit these multiple cofactors is not clear. Here we show that activation by androgen receptor and thyroid hormone receptor is associated with the promoter targeting of SRC family members, p300, SWI/SNF ...
Philip A. Cole, Laurent M. Sachs, Zhi Qing Huang, Jiwen Li, Jiemin Wong   +4 more
openaire   +4 more sources

Enhancing and Stabilizing Hydrogen Catalysis Through [NiFe]‐Hydrogenase Immobilization Within Macroporous Covalent Organic Frameworks

Advanced Functional Materials, EarlyView.
[NiFe]‐hydrogenases efficiently catalyze hydrogen conversion, but their instability limits biotechnological applications. Here it is shown that encapsulating hydrogenase into hierarchical COFs with macro‐ and micropores and functionalized with sulfonic or carboxylic acid groups improves enzyme stability and electron transfer to electrodes.
Islam E. Khalil, Armel F. Tadjoung Waffo, Prasenjit Das, Sagie Katz, Sandra Kunow, Christian Lorent, Yasmine Ziouani, Warisha Tahir, Augustine A. Owusu, Oliver Lenz, Ingo Zebger, Stefan Frielingsdorf, Arne Thomas   +12 more
wiley   +1 more source

Retinoid X receptor γ interacts with peroxisome proliferator-activated receptor-γ to promote browning during adipose tissue differentiation

Adipocyte
Obesity and type 2 diabetes mellitus are global public health challenges. Activating thermogenic adipose tissues, such as brown adipose tissue and beige adipose tissue, could be a promising strategy to combat obesity and consequently obesity-related ...
Defei Chen, Saed Woraikat, Xiong Guo, Fuyu Yang, Chenglin Tang, Fan He, Kun Qian   +6 more
doaj   +1 more source

On cofactored verification of EdDSA signatures [PDF]

International Journal of Electronics and Telecommunications
EdDSA is a Schnorr signature scheme instantiated on top of Edwards curves, which admit fast, constant-time arithmetic, but suffer from the presence of a non-trivial cofactor, where the order of the group of points is a large prime times a small integer ...
Adrian Cinal, Oliwer Sobolewski
doaj   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Analysis of a moving mask approximation for martensitic transformations

, 2018
In this work we introduce a moving mask approximation to describe the dynamics of austenite to martensite phase transitions at a continuum level. In this framework, we prove a new type of Hadamard jump condition, from which we deduce that the deformation
Della Porta, Francesco
core   +1 more source

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

Nucleic Acids Res., 2012
We have developed a new COFACTOR webserver for automated structure-based protein function annotation. Starting from a structural model, given by either experimental determination or computational modeling, COFACTOR first identifies template proteins of ...
Ambrish Roy, Jianyi Yang, Yang Zhang
semanticscholar   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

RUNX1 as a recombinase cofactor

Oncotarget, 2015
The regulation of TCR rearrangements, particularly of TCRδ and TCRβ, plays a decisive role in lymphoid differentiation and oncogenic transformation. Somatic assembly of TCR loci is established through V(D)J recombination during lymphocyte development.
Agata Cieslak, Vahid Asnafi, Dominique Payet-Bornet   +2 more
openaire   +3 more sources

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source