Results 131 to 140 of about 188,158 (291)

Defined Electrosynthetic Microbial Consortia Reveal Electron Transfer Modes Governing Acetate Production

Advanced Science, EarlyView.
Spatially resolved Shewanella–acetogen interactions link DIET and MET pathways to acetate formation, offering a generalizable framework for designing structured, high‐efficiency microbial electrosynthesis systems. Abstract Precise manipulation of interspecies electron transfer (IET) is critical for advancing microbial electrosynthesis (MES) toward ...
Jing Zhang, He Liu, Qihao Cao, Chao Zhang, Min Zhang, Minhua Cui, Yan Zhang, Bo Fu, Hongbo Liu   +8 more
wiley   +1 more source

Site-Specific Bioconjugation of an Organometallic Electron Mediator to an Enzyme with Retained Photocatalytic Cofactor Regenerating Capacity and Enzymatic Activity [PDF]

, 2015
Sung H. Lim, S.I. Yoon, Yong Oock Kim, Inchan Kwon   +3 more
openalex   +1 more source

Cofactor [PDF]

, 2020
openaire   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Investigating operational stability and causes of cofactor release in fold type I amine transaminase. [PDF]

Protein Sci
Feng X, Chau W, Master ER.
europepmc   +1 more source

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

, 1993
Chao-Ming Chiang, Hui Ge, Zhiqiang Wang, Alexander Hoffmann, Robert G. Roeder   +4 more
openalex   +2 more sources

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Uncovering Major Structural and Functional Features of Methyl-Coenzyme M Reductase (MCR) from <i>Methanobrevibacter ruminantium</i> in Complex with Two Substrates. [PDF]

Int J Mol Sci
Chai HH, Park W, Lim D.
europepmc   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Structures of two LarA-like nickel-pincer nucleotide cofactor-utilizing enzymes with a single catalytic histidine residue. [PDF]

Protein Sci
Gatreddi S, Subramanian S, Sui D, Wang T, Urdiain-Arraiza J, Desguin B, Hausinger RP, Parent KN, Hu J.   +8 more
europepmc   +1 more source