Results 151 to 160 of about 188,158 (291)
Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme [PDF]
, 2019 Olga M. Sokolovskaya +5 more
openalex +1 more source
A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
Advanced Science, EarlyView.This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
Ligand metathesis as rational strategy for the synthesis of cubane-type heteroleptic iron–sulfur clusters relevant to the FeMo cofactor [PDF]
, 2018 Gan Xu +5 more
openalex +1 more source
Advanced Science, EarlyView.Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu +8 more
wiley +1 more source
Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization
Frontiers in Bioengineering and Biotechnology, 2022 Jennifer Perrin +3 more
doaj +1 more source
Comparing frequentist and Bayesian methods to identify drivers of pathogen strain invasion: A temporal case study of pertussis in the United States. [PDF]
Infect Dis ModelLecorvaisier F +3 more
europepmc +1 more source
Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H [PDF]
, 1984 Jochem Alsenz +3 more
openalex +1 more source
Advanced Science, EarlyView.This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source