Results 281 to 290 of about 413,042 (378)

PCR‐Free Site‐Directed Mutagenesis on Repetitive Sequences Using Single‐Stranded DNA‐Assisted Double‐Stranded DNA Nicking by DNAzymes

open access: yesAngewandte Chemie International Edition, Accepted Article.
Site‐directed mutagenesis (SDM) is a key driver for many biochemical investigations and biotechnological applications. Despite decades of development, it is still difficult to perform SDM on some sequences, including highly repetitive ones, because polymerase chain reaction (PCR) is often used as the most effective method for SDM, but results in ...
Mingkuan Lyu   +3 more
wiley   +1 more source

Cyanide and Methylisocyanide Binding to the Isolated Iron-Molybdenum Cofactor of Nitrogenase

open access: hybrid, 1989
Steven D. Conradson   +6 more
openalex   +1 more source

Deciphering Tryptophan Oxygenation: Key Modulators of 2‐Oxindole Formation in MarE

open access: yesAngewandte Chemie International Edition, Accepted Article.
MarE, a heme‐dependent aromatic oxygenase with a histidyl axial ligated, catalyzes the monooxygention of β‐methyl‐L‐tryptophan, to form a 2‐oxindole scaffold central to maremycin biosynthesis. Although structurally similar to tryptophan 2,3‐dioxygenase (TDO), which initiates L‐tryptophan catabolism via dioxygenation, MarE exhibits distinct reactivity ...
Romie C. Nguyen, Inchul Shin, Aimin Liu
wiley   +1 more source

Structured Lipids: Synthesis, Genetic Engineering, and Applications

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Lipids are essential to the human body, but some can be harmful. As a result, current research focuses on structured lipids (SLs), which are engineered to have specific fatty acid arrangements. These structural modifications can enhance both nutritional and physical properties.
Chandu S. Madankar   +5 more
wiley   +1 more source

Crystal Structure of an Aldo-keto Reductase MGG_00097 from Magnaporthe grisea. [PDF]

open access: yesPlant Pathol J
Huang X   +8 more
europepmc   +1 more source

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