De novo design of four-helix bundle proteins to bind metalloporphyrin cofactors. [PDF]
Coronado KR, Zhu Y, Mann SI.
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Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian+4 more
wiley +1 more source
Inspired by enzyme cofactors, a CdS‐supported nickel boride@nickel borate core‐shell nanoarchitectured photocatalyst was developed, featuring closely integrated electron/proton acceptors and catalytic sites. This “all‐in‐one” photocatalyst boosted charge separation and facilitated electron–proton cascade transfer, enabling selective co‐synthesis of ...
Shuai Zhang+5 more
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Kinetic Characterization of <i>F</i> <sub>420</sub>-Dependent Sugar-6-Phosphate Dehydrogenase from <i>Cryptosporangium arvum</i>. [PDF]
Aziz A+12 more
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Structural insights and rational design of Pseudomonasputida KT2440 omega transaminases for enhanced biotransformation of (R)-PAC to (1R, 2S)-Norephedrine. [PDF]
Das P, Noronha S, Bhaumik P.
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The biological relevance of potentially toxic metals in freshwater fish. [PDF]
Kovacik A+5 more
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Regioselective Hydration of Terpenes with Cofactor-Independent Carotenoid 1,2-Hydratase. [PDF]
Horz P+6 more
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Hydrogen sulfide-dependent activation of human sulfide quinone oxidoreductase. [PDF]
Roman JV+6 more
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Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms
Mushrooms have learned twice independently how to make the iconic magic mushroom natural product psilocybin. This article introduces the enzymes of the second pathway, found in a fiber cap mushroom. Curiously, the two pathways do not share any reaction, nor do the enzymes show a close relationship, but both pathways proceed via 4‐hydroxytryptamine as a
Tim Schäfer+3 more
wiley +1 more source
Experimental and Computational Evaluation of Nicotinamide Cofactor Biomimetics. [PDF]
Kenney KC+9 more
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