Results 121 to 130 of about 814,206 (314)

Cognition Model in Conceptual Designing [PDF]

open access: yes, 2009
Both design researchers and cognitive scientists have developed various process models to study human creative behaviour in design. The models developed are often based on observations of design processes and analysis of design protocols.
W. Abdelhameed
core  

Mnemonic convergence in the human hippocampus

open access: yesNature Communications, 2016
The ability to form associations between events is the hallmark of episodic memory and is thought to involve the hippocampus. Here the authors use a combination of multivariate pattern and graph theoretical network analyses of functional imaging data in ...
Alexander R. Backus   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

How Perceived Cognitive Style, Metacognitive Monitoring, and Epistemic Cognition Indicate Problem Solving Confidence [PDF]

open access: yes, 2009
The purpose of this exploratory study was to measure perceived cognitive style, metacognitive monitoring, and epistemic cognition according to Kitchener’s (1983) hierarchal model of cognitive processing as an indicator for problem solving ...
Price, Steven Mitchell
core  

Modelling Supernatural Belief: Cognition and Personality [PDF]

open access: yes, 2020
This study aimed to create and test a new model of supernatural belief based on cognition and personality. Two theories of belief in the paranormal were evaluated in two studies: the Cognitive Deficits Hypothesis and the Psychodynamic Functions ...
Baker, I.   +3 more
core  

“R” you getting this? Factors contributing to the public’s understanding, evaluation, and use of basic reproduction numbers for infectious diseases

open access: yesBMC Public Health
Background We (1) examined the effects of evaluative labels and visual aids on people’s understanding, evaluation, and use of the COVID-19 reproduction number (or “r-number”), (2) examined whether people’s perceived susceptibility and (intended ...
Ruben D. Vromans   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Understanding individual neurodegenerative progression in Parkinson’s disease through normative modelling

open access: yesScientific Reports
Parkinson’s disease (PD) is a neurodegenerative disorder with motor symptoms (e.g., bradykinesia, tremors) and non-motor symptoms (e.g., cognitive deficits).
Charlotte Fraza   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy