Results 121 to 130 of about 995,391 (302)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
The Extended Mind and Network-Enabled Cognition
In thinking about the transformative potential of network technologies with respect to human cognition, it is common to see network resources as playing a largely assistive or augmentative role. In this paper we propose a somewhat more radical vision. We
Smart, Paul +4 more
core +1 more source
Cognition Model in Conceptual Designing
, 2009 Both design researchers and cognitive scientists have developed various process models to study human creative behaviour in design. The models developed are often based on observations of design processes and analysis of design protocols.
W. Abdelhameed
core
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
, 2016 Bienvenue sur le carnet du groupe Culture Cognition Affectivité, un ensemble de chercheurs et étudiants réunis autour de la thématique Culture Cognition Affectivité, menée par Nadja Acioly-Régnier.
Marie B.
core
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Pre-saccadic Attention (and not Arousal) modulates the Size-Eccentricity Effect
Scientific ReportsPeripherally located objects are often perceived to be smaller than centrally located objects. This perceptual phenomenon, known as the Size-Eccentricity Effect (SEE), is mainly due to the structural properties of the visual system and is further ...
Jad Laaboudi +2 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source