Results 101 to 110 of about 995,391 (302)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Codifying distributed cognition: a case study of emergency medical dispatch [PDF]
, 2004 The theory of distributed cognition is recognised as being relevant to system analysis and design but it has lacked visibility for practice. In this paper I develop a codified method of analysis based on distributed cognition which provides both ...
Furniss, D.
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The relationship between trait curiosity and cognitive reserve in younger and older adults
Scientific ReportsUnderstanding individual differences in cognitive reserve is key to predicting, and potentially influencing, factors that promote healthy cognitive aging.
Iris Wiegand +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Scientific DataThe SpiderPhy dataset is a dataset of physiological, psychometric, and behavioral data from subclinical spider fearful individuals (N = 54) who underwent exposure to spider stimuli.
Cindy S. Lor +9 more
doaj +1 more source
Mnemonic convergence in the human hippocampus
Nature Communications, 2016 The ability to form associations between events is the hallmark of episodic memory and is thought to involve the hippocampus. Here the authors use a combination of multivariate pattern and graph theoretical network analyses of functional imaging data in ...
Alexander R. Backus +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
, 2006 This paper investigates the difference of spatial perception and cognition between virtual and real architectural environments. Specifically, three different aspects have been studied, concerning the live perception and cognition of a complex actual ...
S. Mikrou +3 more
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