Results 81 to 90 of about 995,391 (302)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cognition

, 2018
L’article offre un aperçu de l’élaboration épistémologique du concept de cognition dans la revue Hermès. L’engagement de la revue dans le champ des sciences de la cognition offre les gages d’une résistance au scientisme qui menace, et propose au lecteur ...
Besnier, Jean-Michel
core  

Gender differences in spatial cognition [PDF]

, 2009
Spatial abilities, such as wayfinding and memorizing object locations, seem to be equally important for every individual. Yet both common belief and scientific literature claim that men and women differ in these abilities.
de Goede, M., Neuropsychology, psychopathology and cognition, Afd Psychologische functieleer   +2 more
core   +1 more source

FRONTIERS IN COGNITION

, 2011
Frontiers in Cognition publishes articles on the most outstanding discoveries across the research spectrum of ...
DI PELLEGRINO, GIUSEPPE
core   +1 more source

Exploring the electrophysiological correlates of the default-mode network with intracerebral EEG

Frontiers in Systems Neuroscience, 2010
While functional imaging studies allow for a precise spatial characterization of resting state networks, their neural correlates and thereby their fine-scale temporal dynamics remain elusive.
Karim Jerbi, Karim Jerbi, Juan R Vidal, Juan R Vidal, Tomas Ossandon, Tomas Ossandon, Sarang S Dalal, Sarang S Dalal, Julien Jung, Julien Jung, Dominique Hoffmann, Lorella Minotti, Olivier Bertrand, Olivier Bertrand, Philippe Kahane, Jean-Philippe Lachaux, Jean-Philippe Lachaux   +16 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Semantic associative abilities and executive control functions predict novelty and appropriateness of idea generation

Communications Biology
Novelty and appropriateness are two fundamental components of creativity. However, the way in which novelty and appropriateness are separated at behavioral and neural levels remains poorly understood.
Xueyang Wang, Qunlin Chen, Kaixiang Zhuang, Jingyi Zhang, Robert A. Cortes, Daniel D. Holzman, Li Fan, Cheng Liu, Jiangzhou Sun, Xianrui Li, Yu Li, Qiuyang Feng, Hong Chen, Tingyong Feng, Xu Lei, Qinghua He, Adam E. Green, Jiang Qiu   +17 more
doaj   +1 more source

Generating normative data from web-based administration of the Cambridge Neuropsychological Test Automated Battery using a Bayesian framework

Frontiers in Digital Health
IntroductionNormative cognitive data can distinguish impairment from healthy cognitive function and pathological decline from normal ageing. Traditional methods for deriving normative data typically require extremely large samples of healthy participants,
Elizabeth Wragg, Caroline Skirrow, Caroline Skirrow, Pasquale Dente, Jack Cotter, Peter Annas, Peter Annas, Milly Lowther, Milly Lowther, Rosa Backx, Jenny Barnett, Jenny Barnett, Fiona Cree, Jasmin Kroll, Francesca Cormack   +14 more
doaj   +1 more source

On Measuring Cognition and Cognitive Augmentation

, 2018
15 pages, 4 figures, multiple ...
openaire   +3 more sources