Results 81 to 90 of about 1,773,581 (311)

Pharmacokinetics and metabolic effects of ketone monoester supplementation: The first simultaneous CKM and CGM study under normal diet and activities

Metabolism Open
Exogenous ketone supplementation has gained attention for its potential health and performance benefits, yet its real-world pharmacokinetics and metabolic effects remain underexplored. This study investigated the pharmacokinetics of ketone monoester (KME)
Toshiya Miyatsu, Connor Tate, Jeremy McAdam, Chandler Massey, Timothy Broderick   +4 more
doaj   +1 more source

Task modulation of brain responses in visual word recognition as studied using EEG/MEG and fMRI

Frontiers in Human Neuroscience, 2013
Do task demands change the way we extract information from a stimulus, or only how we use this information for decision making? In order to answer this question for visual word recognition, we used EEG/MEG as well as fMRI to determine the latency ranges ...
Yuanyuan eChen, Yuanyuan eChen, Matthew H Davis, Friedemann ePulvermüller, Friedemann ePulvermüller, Olaf eHauk   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorder

BMC Pediatrics
Background Understanding the priorities of parents of children and adolescents with autism spectrum disorder (ASD) is crucial for implementing evidence-based programs. This study aims to identify the functional priorities of parents of Brazilian children
Amanda Aparecida Alves Cunha Nascimento, Deisiane Oliveira Souto, Thalita Karla Flores Cruz, Arthur Felipe Barroso de Lima, Gabriela Silva Oliveira, Vitor Geraldi Haase   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Semantic associative abilities and executive control functions predict novelty and appropriateness of idea generation

Communications Biology
Novelty and appropriateness are two fundamental components of creativity. However, the way in which novelty and appropriateness are separated at behavioral and neural levels remains poorly understood.
Xueyang Wang, Qunlin Chen, Kaixiang Zhuang, Jingyi Zhang, Robert A. Cortes, Daniel D. Holzman, Li Fan, Cheng Liu, Jiangzhou Sun, Xianrui Li, Yu Li, Qiuyang Feng, Hong Chen, Tingyong Feng, Xu Lei, Qinghua He, Adam E. Green, Jiang Qiu   +17 more
doaj   +1 more source

LIDA: A Working Model of Cognition [PDF]

, 2006
In this paper we present the LIDA architecture as a working model of cognition. We argue that such working models are broad in scope and address real world problems in comparison to experimentally based models which focus on specific pieces of cognition.
Baars, Bernard J., Franklin, Stan, Ramamurthy, Uma, S. K., D'Mello   +3 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Distributed Processes, Distributed Cognizers and Collaborative Cognition [PDF]

, 2005
Cognition is thinking; it feels like something to think, and only those who can feel can think. There are also things that thinkers can do. We know neither how thinkers can think nor how they are able do what they can do.
Harnad, Stevan
core   +2 more sources

Exploring the electrophysiological correlates of the default-mode network with intracerebral EEG

Frontiers in Systems Neuroscience, 2010
While functional imaging studies allow for a precise spatial characterization of resting state networks, their neural correlates and thereby their fine-scale temporal dynamics remain elusive.
Karim Jerbi, Karim Jerbi, Juan R Vidal, Juan R Vidal, Tomas Ossandon, Tomas Ossandon, Sarang S Dalal, Sarang S Dalal, Julien Jung, Julien Jung, Dominique Hoffmann, Lorella Minotti, Olivier Bertrand, Olivier Bertrand, Philippe Kahane, Jean-Philippe Lachaux, Jean-Philippe Lachaux   +16 more
doaj   +1 more source