Results 91 to 100 of about 1,773,581 (311)

Cohabitation: Computation at 70, Cognition at 20 [PDF]

, 2009
Zenon Pylyshyn cast cognition's lot with computation, stretching the Church/Turing Thesis to its limit: We had no idea how the mind did anything, whereas we knew computation could do just about everything. Doing it with images would be like doing it with
Harnad, Stevan
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Saccadic velocity in the new suppression head impulse test (SHIMP): a new indicator of horizontal vestibular canal paresis and of vestibular compensation

Frontiers in Neurology, 2016
ObjectiveTo determine whether saccadic velocity in the suppression head impulse paradigm (SHIMP) test is a reliable indicator of vestibular loss at the acute and at the chronic stage in patients suffering from different vestibular pathologies.Methods35 ...
Qiwen Shen, Christophe Magnani, Olivier Sterkers, Georges Lamas, Pierre-Paul Vidal, Julien Sadoun, Ian S Curthoys, Catherine De Waele, Catherine De Waele   +8 more
doaj   +1 more source

The effects of context processing on social cognition impairments in adults with Aspergers syndrome [PDF]

, 2014
Social cognition—the basis of all communicative and otherwise interpersonal relationships—is embedded in specific contextual circumstances which shape intrinsic meanings.
Báez Buitrago, Sandra Jimena, Ibañez, Agustin Mariano   +1 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Generating normative data from web-based administration of the Cambridge Neuropsychological Test Automated Battery using a Bayesian framework

Frontiers in Digital Health
IntroductionNormative cognitive data can distinguish impairment from healthy cognitive function and pathological decline from normal ageing. Traditional methods for deriving normative data typically require extremely large samples of healthy participants,
Elizabeth Wragg, Caroline Skirrow, Caroline Skirrow, Pasquale Dente, Jack Cotter, Peter Annas, Peter Annas, Milly Lowther, Milly Lowther, Rosa Backx, Jenny Barnett, Jenny Barnett, Fiona Cree, Jasmin Kroll, Francesca Cormack   +14 more
doaj   +1 more source

Child-Robot Interactions for Second Language Tutoring to Preschool Children

Frontiers in Human Neuroscience, 2017
In this digital age social robots will increasingly be used for educational purposes, such as second language tutoring. In this perspective article, we propose a number of design features to develop a child-friendly social robot that can effectively ...
Paul Vogt, Mirjam de Haas, Chiara de Jong, Peta Baxter, Emiel Krahmer   +4 more
doaj   +1 more source

Culture in Mind - An Enactivist Account: Not Cognitive Penetration But Cultural Permeation [PDF]

Advancing a radically enactive account of cognition, we provide arguments in favour of the possibility that cultural factors permeate rather than penetrate cognition, such that cognition extensively and transactionally incorporates cultural factors ...
Gallagher, Shaun, Hipólito, Inês, Hutto, Daniel D.   +2 more
core  

Radically enactive high cognition [PDF]

, 2018
I advance the Radically Enactive Cognition (REC) program by developing Hutto & Satne’s (2015) and Hutto & Myin’s (2017) idea that contentful cognition emerges through sociocultural activities, which require a contentless form of ...
Rolla, Giovanni
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source