Results 71 to 80 of about 1,010,398 (257)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Distributed cognition: cognizing, autonomy and the Turing Test
, 2006 Some of the papers in this special issue distribute cognition between what is going on inside individual cognizers’ heads and their outside worlds; others distribute cognition among different individual cognizers.
Harnad, Steven +3 more
core +1 more source
BMC PediatricsBackground Understanding the priorities of parents of children and adolescents with autism spectrum disorder (ASD) is crucial for implementing evidence-based programs. This study aims to identify the functional priorities of parents of Brazilian children
Amanda Aparecida Alves Cunha Nascimento +5 more
doaj +1 more source
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
Nature Communications, 2019 Kleefstra syndrome is a neurodevelopmental disorder associated with hapoinsufficiency of the histone methyltransferase EHMT1. Here the authors show using induced pluripotent cells-derived neurons from patients that network dysfunction occurs and is due ...
Monica Frega +18 more
doaj +1 more source
Exploring the electrophysiological correlates of the default-mode network with intracerebral EEG
Frontiers in Systems Neuroscience, 2010 While functional imaging studies allow for a precise spatial characterization of resting state networks, their neural correlates and thereby their fine-scale temporal dynamics remain elusive.
Karim Jerbi +16 more
doaj +1 more source
, 2018 L’article offre un aperçu de l’élaboration épistémologique du concept de cognition dans la revue Hermès. L’engagement de la revue dans le champ des sciences de la cognition offre les gages d’une résistance au scientisme qui menace, et propose au lecteur ...
Besnier, Jean-Michel
core
Développement ontogénétique de la cognition humaine : champs de recherche, méthodes et perspectives
, 2020 International audienceFrom its origins, the study of the development of human cognition from an ontogenetic point of view (i.e. from birth to adulthood) has been confronted to both theoretical and methodological issues.
Rat-Fischer, Lauriane
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Independent evolution of similar complex cognitive skills : the importance of embodied degrees of freedom [PDF]
, 2014 Recent years have seen acknowledgment from a number of researchers that similarities appear to exist in complex cognitive skills of distantly related species – most notably in corvids, parrots, delphinids, and great apes. Discoveries on complex cognitive
Kabadayi, Can +9 more
core +2 more sources