Results 181 to 190 of about 2,005,242 (383)
Cognition of the relation between an event and a circumstance understood to explain the event [PDF]
, 1974 Gordon Bear
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Competing fairness ideals underlie wealth inequality across decision contexts
Scientific ReportsWealth inequality is one of the most profound challenges confronting society today. However, an important issue in addressing inequality lies in formalizing the diversity of individual perspectives regarding what constitutes a fair distribution of ...
Inge Huijsmans +4 more
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Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
SpiDa-MRI: behavioral and (f)MRI data of adults with fear of spiders
Scientific DataNeuroimaging has greatly improved our understanding of phobic mechanisms. To expand on these advancements, we present data on the heterogeneity of neural patterns in spider phobia combined with various psychological dimensions of spider phobia, using ...
Mengfan Zhang +8 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
A STUDY OF FIGURE COGNITION OF FEEBLE-MINDED CHILDREN
, 1969 Tositaka Tanaka
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Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Both slow wave and rapid eye movement sleep contribute to emotional memory consolidation
Communications BiologySleep supports memory consolidation, but the specific roles of different sleep stages in this process remain unclear. While rapid eye movement sleep (REM) has traditionally been linked to the processing of emotionally charged material, recent evidence ...
Cagri Yuksel +8 more
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Children's use of social conceptions: Toward a dynamic model of social cognition
, 1978 E. W. Cooney, Robert I. Selman
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