Results 101 to 110 of about 2,804,955 (318)
Frontiers in Psychiatry, 2012 Decreased cognitive ability is a significant problem in schizophrenia, and it has been proposed that augmentation of antipsychotics with 5HT1A receptor agonists may improve cognitive performance.
Peter H Silverstone +2 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Why it is important to build robots capable of doing science
, 2002 Science, like any other cognitive activity, is grounded in the sensorimotor interaction of our bodies with the environment. Human embodiment thus constrains the class of scientific concepts and theories which are accessible to us.
Florian, Razvan V.
core
An Investigation into the Development of English Materials for Delivery via Mobile [PDF]
Interdisciplinary Journal of Virtual Learning in Medical Sciences, 2014 Introduction: No longer thought to be value-neutral, textbooks and other materials used in language learning, generally, present a certain way of looking at the world.
Saeed Khazaie +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Design activities: how to analyze cognitive effort associated to cognitive treatments?
, 2003 Working memory issues are important in many real activities. Thus, measuring cognitive effort (or mental load) has been a main research topic for years in cognitive ergonomics, though no consensual method to study such aspect has been proposed.
Bonnardel, N, Piolat, A
core
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Neuroethical Issues in Cognitive Enhancement: the Undergraduates’ Point of View
, 2018 To date, legitimacy of the application of cognitive enhancement programs to healthy individuals is still fueling neuroethics discussions. The aim of the present investigation is analyzing naïve conceptions of the ethical implications of different prac ...
Cancer, Alice, Antonietti, Alessandro
core +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source