Results 91 to 100 of about 5,782,571 (261)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Methods for stimulating cognitive abilities used by students

open access: yesOne Health & Risk Management
Introduction. The modern workplace requires workers to have broad cognitive and affective abilities. For continuous progress and societal improvement, students’ education plays a crucial role, and for this, students need a high level of cognitive ...
Mariana CERNITANU
doaj  

If You Are So Smart, Why Aren't You an Entrepreneur? Returns to Cognitive and Social Ability: Entrepreneurs versus Employees [PDF]

open access: yes
How valuable are cognitive and social abilities for entrepreneurs’ incomes as compared to employees? We answer three questions: (1) To what extent does a composite measure of ability affect an entrepreneur's earnings relative to employees?
Hartog, Joop   +2 more
core  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

The Merits of Ability in Developing and Developed Countries [PDF]

open access: yes
Different economic characteristics between developing and developed countries may require worker with different skills, resulting in different returns to the same ability.
Daniel Suryadarma
core  

Metonymic processing: a cognitive ability relevant to translators, editors and language teachers [PDF]

open access: yes, 2010
‘Metonymic processing’, the ability to recognize relatedness through shared features, associations or part-whole relations, is a basic cognitive ability, which can be listed along with other abilities, such a matching, selecting, ordering and recombining.
Denroche, C.
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Cognitive ability and risk aversion: A systematic review and meta analysis

open access: yesJudgment and Decision Making, 2019
Are highly intelligent people less risk averse? Over the last two decades scholars have argued the existence of a negative relationship between cognitive ability and risk aversion.
Lau Lilleholt
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Are neoliberals more susceptible to bullshit?

open access: yesJudgment and Decision Making, 2016
We conducted additional analyses of Pennycook et al.’s (2015, Study 2) data to investigate the possibility that there would be ideological differences in “bullshit receptivity” that would be explained by individual differences in cognitive style and ...
Joanna Sterling   +2 more
doaj   +1 more source

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