Results 111 to 120 of about 2,225,872 (200)

A Speech-Based Mobile Screening Tool for Mild Cognitive Impairment: Technical Performance and User Engagement Evaluation

Bioengineering
Traditional screening methods for Mild Cognitive Impairment (MCI) face limitations in accessibility and scalability. To address this, we developed and validated a speech-based automatic screening app implementing three speech–language tasks with user ...
Rukiye Ruzi, Yue Pan, Menwa Lawrence Ng, Rongfeng Su, Lan Wang, Jianwu Dang, Liwei Liu, Nan Yan   +7 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Accessibility and the Journey to Work [PDF]

This study analyzes the effect of accessibility to jobs and houses at both the home and work ends of trips on commuting duration for respondents to a household travel survey in metropolitan Washington, DC.
David Levinson
core  

Assessing Inclusive Park Design in Ankara, Türkiye: A Comparative E-PIDI Analysis of the Capital National Garden and National Botanical Garden

Land
Urban parks can promote equitable access to recreation, nature and social interaction when their design responds to diverse physical, sensory, cognitive, social and environmental needs.
Mertkan Fahrettin Tekinalp, Gülbin Çetinkale Demirkan   +1 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Perceived accessibility: Literature review and future prospects

Journal of Transport and Land Use
Perceived accessibility can fully present the cognitive status of different individuals and produce potential positive results. However, the literature on perceived accessibility is scattered across disciplines, which leads to problems of inconsistency ...
Xiaona Ma, Fasheng Cui
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Development and Application of an Activity Based Space-Time Accessibility Measure for Individual Activity Schedules [PDF]

Accessibility is an important aspect of human existence impacting on our notion of society equity and justice. It plays an important role in a number of existing theories of spatial and travel behaviour in addition to affecting the rate and the pattern ...
Olu Ashiru, John Polak, Robert B. Noland
core  

Technical Evaluation Report 32: Using Internet Audio to Enhance Online Accessibility

International Review of Research in Open and Distributed Learning, 2004
What constitutes online accessibility? Vanderheiden, Harkins and Barnicle (2002) indicate that accessibility involves the ability to use online content without vision, without hearing, without pointing or manipulation, and without speech by persons with ...
Linda Matula Schwartz
doaj