Results 51 to 60 of about 590,203 (332)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad   +7 more
wiley   +1 more source

Comparing the effectiveness of cognitive-behavioral therapy and acceptance and commitment based therapy on health anxiety in nurses

open access: yesروانشناسی و روانپزشکی شناخت
Introduction: Although some researches indicate that cognitive-behavioral therapy is more effective than other treatments, but the need to compare cognitive-behavioral therapy with an approach such as acceptance and commitment-based therapy can be seen ...
Naghmeh Ashoori
doaj   +1 more source

The Efficacy of Cognitive Behavioral Group-Therapy Alone and plus Family Psycho-Education on the Treatment of Major Depression Disorder Symptoms in Females [PDF]

open access: yes, 2012
: Background & Aims: Major depression is one of the common psychiatric disorders imposing negative effects on patients and their families. There are several treatment methods for depression.
Solati Dehkordi K., Mobasheri M.,
core  

Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova   +3 more
wiley   +1 more source

The investigating comparison of the efficacy of cognitive-behavioral therapy (CBT) and mindfulness-based cognitive-behavioral therapy on perfectionism, psychological distress, and pain intensity in patients with migraine headache

open access: yesمجله علوم روانشناختی, 2023
Background: Pain as a multifaceted phenomenon is associated with great psychological, social and physical suffering and reduces the performance of the individual in society. Among these, Migraine headaches are one of the most common types of pain and the
Marziyeh Sargoli Shahkhaseh   +2 more
doaj  

Psychological Treatments for Borderline Personality Disorder: A Review of Cognitive-Behavioral Oriented Therapies

open access: yesActa Médica Portuguesa, 2017
Introduction: Borderline personality disorder is the most common personality disorder, with a global prevalence rate between 1.6% and 6%. It is characterized by affective disturbance and impulsivity, which lead to a high number of self-harm behaviors and
Sofia Marques   +2 more
doaj   +1 more source

Log in and breathe out: efficacy and cost-effectiveness of an online sleep training for teachers affected by work-related strain-study protocol for a randomized controlled trial [PDF]

open access: yes, 2013
Background: Insomnia and work-related stress often co-occur. Both are associated with personal distress and diminished general functioning, as well as substantial socio-economic costs due to, for example, reduced productivity at the work place and ...
Berking, M.   +5 more
core   +4 more sources

Precision‐Optimised Post‐Stroke Prognoses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope   +4 more
wiley   +1 more source

Trauma-Focused Interventions: A Clinical Practice Analysis [PDF]

open access: yes, 2018
This paper presents a systematic review of trauma-treatment interventions, which have different theoretical perspectives on trauma etiology and its application. The empirical findings of these trauma treatment therapies are presented.
Carbajal, Jose
core   +1 more source

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