Results 111 to 120 of about 4,029,695 (306)

Dynamicity of brain network organization & their community architecture as characterizing features for classification of common mental disorders from whole-brain connectome

open access: yesTranslational Psychiatry
The urgency of addressing common mental disorders (bipolar disorder, attention-deficit hyperactivity disorder (ADHD), and schizophrenia) arises from their significant societal impact. Developing strategies to support psychiatrists is crucial.
Nisha Chetana Sastry, Arpan Banerjee
doaj   +1 more source

Task-dependent representations of stimulus and choice in mouse parietal cortex

open access: yesNature Communications, 2018
The precise role of PPC in transforming sensory signals to relevant actions is not yet clear. Here, the authors show that unlike V1, which is largely driven by visual input, PPC is strongly task-dependent and exhibits a mixture of stimulus and choice ...
Gerald N. Pho   +4 more
doaj   +1 more source

Mirror visual feedback-induced performance improvement and the influence of hand dominance

open access: yesFrontiers in Human Neuroscience, 2016
Mirror Visual Feedback (MVF) is a promising technique in clinical settings that can be used to augment performance of an untrained limb. Several studies with healthy volunteers and patients using transcranial magnetic stimulation (TMS) or functional ...
Viola eRjosk   +10 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Author Correction: Dissonance encoding in human inferior colliculus covaries with individual differences in dislike of dissonant music

open access: yesScientific Reports, 2021
Seung-Goo Kim   +4 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Human and chimpanzee shared and divergent neurobiological systems for general and specific cognitive brain functions. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
van den Heuvel MP   +10 more
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy