CSF sTREM2: Marking the tipping point between preclinical AD and dementia? [PDF]
, 2016 Biomarkers for Alzheimer's disease (AD) have improved our understanding of the temporal sequence of biological events that lead to AD dementia (Jack et al, 2013).
Holtzman, David M, Schindler, Suzanne E
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Performance Variability During a Multitrial List-Learning Task as a Predictor of Future Cognitive Decline in Healthy Elders [PDF]
, 2014 Introduction: In clinical settings, neuropsychological test performance is traditionally evaluated with total summary scores (TSS). However, recent studies demonstrated that indices of intraindividual variability (IIV) yielded unique information ...
Durgerian, Sally +8 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Research priorities for cognitive decline in India
Journal of Geriatric Mental Health, 2016 The elderly population with cognitive decline is increasing at an alarming rate in developing countries such as India. There is a paucity of basic clinical research in the field of cognitive decline dealing with areas of prevalence, etiology, diagnosis ...
Jahnavi S Kedare, Chetan D Vispute
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Screening for subjective cognitive decline in the elderly via subjective cognitive complaints and informant-reported questionnaires: a systematic review [PDF]
, 2021 Sara Wasef +10 more
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ΔFosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer\u27s Disease. [PDF]
, 2017 Alzheimer\u27s disease (AD) is characterized by cognitive decline and 5- to 10-fold increased seizure incidence. How seizures contribute to cognitive decline in AD or other disorders is unclear.
Aschmies, Suzan +14 more
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Aging, Cognitive Decline and Hearing Loss: Effects of Auditory Rehabilitation and Training with Hearing Aids and Cochlear Implants on Cognitive Function and Depression among Older Adults [PDF]
, 2016 A growing interest in cognitive effects associated with speech and hearing processes is spreading throughout the scientific community essentially guided by evidence that central and peripheral hearing loss is associated with cognitive decline.
Benatti, Alice +10 more
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The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Prevention of cognitive decline: Lifestyle and other issues
Journal of Geriatric Mental Health, 2016 Ageing often leads to decline in cognitive abilities. Significant cognitive impairment leads to functional impairment and need for care. Prevention of cognitive decline and delaying its progression would help to reduce the need for long-term care.
Cyriac George, Shijin A Ummar, K S Shaji
doaj +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source