Emerging Nanotechnology Strategies for Obesity Therapy
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang+5 more
wiley +1 more source
Association of psychological stress and subjective cognitive decline. [PDF]
Ramakrishnan M+3 more
europepmc +1 more source
Effects of Blood Pressure Lowering With Perindopril and Indapamide Therapy on Dementia and Cognitive Decline in Patients With Cerebrovascular Disease [PDF]
Christophe Tzourio+6 more
openalex +1 more source
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle+8 more
wiley +1 more source
CSF Biomarker-Based Cognitive Trajectories in Parkinson's Disease-Subjective Cognitive Decline. [PDF]
Rodriguez-Antiguedad J+7 more
europepmc +1 more source
Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease [PDF]
Clive Holmes
openalex +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
The associations between cerebral microhemorrhages and cognitive decline across Alzheimer's continuum. [PDF]
Khaledian H+11 more
europepmc +1 more source
Can vitamin supplements prevent cognitive decline and dementia in old age? [PDF]
Mary N. Haan
openalex +1 more source
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo+10 more
wiley +1 more source