Results 111 to 120 of about 346,998 (261)

Social cognitive deficits and their relationship with clinical symptoms in schizophrenia. [PDF]

Schizophrenia (Heidelb)
He D, Zhang D, Ding Y, Wang X, Xing Y, Li T, Liu Z, Zhou C, Mao Z, Wang Y, Zhao L, Li F, Zhou F, Dong F, Wang C, Bo Q.   +15 more
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Neuroinflammation and white matter microstructure as mediators of cognitive deficits in offspring of parents with bipolar disorder. [PDF]

Brain Commun
Li X, Zou W, Shao R, Lu W, Chao L, Zhao X, Su KP, Lin K.   +7 more
europepmc   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Multidimensional cognitive deficits in the typical and atypical variants of Alzheimer's disease [PDF]

Alzheimers Dement
Henderson S, Murley A, Cope T, Bowns L, Malpetti M, Patterson K, Rowe J, Ralph M.   +7 more
europepmc   +2 more sources

TSPO contributes to neuropathology and cognitive deficits in Alzheimer's disease. [PDF]

J Neuroinflammation
Ceyzériat K, Badina AM, Abjean L, Meyer L, Bouteldja F, Balkota M, Amossé Q, Prudhomme O, Middleton RJ, Liu GJ, Banati RB, Zilli T, Lathuiliere A, Owen D, Maechler P, Garibotto V, Tsartsalis S, Millet P, Tournier BB.   +18 more
europepmc   +2 more sources

Adult-Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits. [PDF]

Ann Clin Transl Neurol
Yeow D, McKern N, Oxenham V, Ahmad K, Ahmad O.   +4 more
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Neonatal sevoflurane exposure disrupts the lung-brain axis and drives microglial neuroinflammation and cognitive deficits. [PDF]

J Neuroinflammation
Liang L, Cao S, Zhao Y, Liu B, Wang J, Gong P, Wang Y, Hao G, ZhangMu X, Lu N, Zhang H, Wu S, Kuang F, Zhang H.   +13 more
europepmc   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source