Results 1 to 10 of about 2,903,135 (304)

Evaluation of the determinants of cognitive dysfunction in patients with multiple sclerosis

open access: yesMiddle East Current Psychiatry, 2022
Background Cognitive dysfunction is common among patients with multiple sclerosis (MS); however, the determinants of cognitive dysfunction are still unknown.
Alireza Haji Seyed Javadi   +2 more
doaj   +1 more source

CA3 Induces Apoptosis of Hepatocellular Carcinoma HepG2 Cells and Related Mechanism

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To investigate the effect of CA3(CIL56) on the proliferation and apoptosis of hepatocellular carcinoma HepG2 cells and its mechanism. Methods HepG2 cells were cultured in vitro and treated with different concentrations of CA3 (0, 0.25, 0.5, 1.0,
ZHANG Shuwen   +3 more
doaj   +1 more source

Postoperative Cognitive Dysfunction

open access: yesIndian Journal of Critical Care Medicine, 2019
Cognitive dysfunction is a common complication in primary or metastatic brain tumors and can be correlated to disease itself or various treatment modalities. The symptoms of cognitive deficits may include problems with memory, attention and information processing.
Kapoor, Indu   +2 more
openaire   +2 more sources

Postoperative cognitive dysfunction [PDF]

open access: yesF1000 Medicine Reports, 2009
Postoperative cognitive dysfunction (POCD) refers to a deterioration in cognition noted to occur after surgery and anesthesia. Recent studies have demonstrated a number of correlates and risk factors for this condition, although much remains to be elucidated in terms of the true incidence, etiology, prevention, and treatment.
openaire   +2 more sources

Serum cystatin C levels are negatively correlated with post-stroke cognitive dysfunction

open access: yesNeural Regeneration Research, 2020
Stroke is the leading cause of death and long-term disability worldwide, and cognitive impairment and dementia are major complications of ischemic stroke. Cystatin C (CysC) has been found to be a neuroprotective factor in animal studies.
Dao-Xia Guo   +14 more
doaj   +1 more source

Integrated Profiling of DEHP-Induced Hippocampal Neurotoxicity in Adult Female Rats Based on Transcriptomic and Neurobiological Analyses

open access: yesToxics
Di-2-ethylhexyl phthalate (DEHP) is a widely used plasticizer with recognized sex-dependent neurotoxicity. However, research on adult neurotoxicity is scarce, especially in females.
Jing Bai   +7 more
doaj   +1 more source

The Role of Gut Microbiota in Mice With Bile Duct Ligation-Evoked Cholestatic Liver Disease-Related Cognitive Dysfunction

open access: yesFrontiers in Microbiology, 2022
The pathogenesis of Hepatic Encephalopathy (HE) is complex and multifactorial. The development of metagenomics sequencing technology led to show the significant role of gut microbiota in the pathogenesis of cognitive dysfunction, which paved the way for ...
Bowen Yang   +5 more
doaj   +1 more source

GLCCI1 alleviates GRP78-initiated endoplasmic reticulum stress-induced apoptosis of retinal ganglion cells in diabetic retinopathy by upregulating and interacting with HSP90AB1

open access: yesScientific Reports
Retinal ganglion cells (RGCs) are among the first neurons to undergo apoptosis in diabetic retinopathy (DR), with their relationship to endoplasmic reticulum stress (ERS)-induced apoptosis still unclear. While glucocorticoid-induced transcript 1 (GLCCI1)
Jiayou Liu   +10 more
doaj   +1 more source

Salidroside alleviates ferroptosis of retinal ganglion cells in db/db mice

open access: yesFood Science and Human Wellness
Salidroside (Sal), is one of the important food supplements from the traditional Chinese medicine Integripetal rhodiola herb, encapsulating significant anti-oxidative stress, anti-ferroptosis, and neuroprotective attributes.
Wenqiang Liu   +16 more
doaj   +1 more source

Microvascular Dysfunction and Cognitive Impairment [PDF]

open access: yesCellular and Molecular Neurobiology, 2016
The impact of vascular risk factors on cognitive function has garnered much interest in recent years. The appropriate distribution of oxygen, glucose, and other nutrients by the cerebral vasculature is critical for proper cognitive performance. The cerebral microvasculature is a key site of vascular resistance and a preferential target for small vessel
T Michael, De Silva, Frank M, Faraci
openaire   +2 more sources

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