Results 251 to 260 of about 3,053,942 (361)

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li   +8 more
wiley   +1 more source

Gestational Age and Cognitive Development in Childhood.

open access: yesJAMA Netw Open
Nivins S, Padilla N, Kvanta H, Ådén U.
europepmc   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

open access: yesAdvanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang   +4 more
wiley   +1 more source

Digital Device Usage and Childhood Cognitive Development: Exploring Effects on Cognitive Abilities. [PDF]

open access: yesChildren (Basel)
Clemente-Suárez VJ   +6 more
europepmc   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim   +19 more
wiley   +1 more source

The Childhood Opportunity Index 2.0: Factor Structure in 9-10 Year Olds in the Adolescent Brain Cognitive Development Study. [PDF]

open access: yesInt J Environ Res Public Health
Harris JC   +4 more
europepmc   +1 more source

Improving cognitive development of low‐birth‐weight premature infants with the COPE program: A pilot study of the benefit of early NICU intervention with mothers [PDF]

open access: bronze, 2001
Bernadette Mazurek Melnyk   +11 more
openalex   +1 more source

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