Results 41 to 50 of about 738,624 (262)

Understanding racial bias through electroencephalography

open access: yesBMC Psychology, 2023
Research on racial bias in social and cognitive psychology has focused on automatic cognitive processes such as categorisation or stereotyping. Neuroimaging has revealed differences in the neural circuit when processing social information about one’s own
Mirella Manfredi   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Differential neural representations of syntactic and semantic information across languages in Chinese-English bilinguals

open access: yesNeuroImage
Bilingual individuals manage multiple languages that align in conceptual meaning but differ in forms and structures. While prior research has established foundational insights into the neural mechanisms in bilingual processing, the extent to which the ...
Zeqi Hou   +4 more
doaj   +1 more source

German and English Bodies: No Evidence for Cross-Linguistic Differences in Preferred Orthographic Grain Size

open access: yesCollabra: Psychology, 2017
Previous studies have found that words and nonwords with many body neighbours (i.e., words with the same orthographic body, e.g., 'cat, brat, at') are read faster than items with fewer body neighbours.
Xenia Schmalz   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Role of neurovascular uncoupling in cognitive decline induced by metabolic disturbances: vascular explorations in a mice model

open access: yesCerebral Circulation - Cognition and Behavior
Introduction: A link between vascular risk factors caused by metabolic disorders in mid-life and the onset of cognitive impairments has been evidenced. Our team has demonstrated that, in a mice model, a cognitive decline occurred after 6 months of high ...
Manon Haas   +5 more
doaj   +1 more source

Positive Effects of Mindfulness-Based Training on Energy Maintenance and the EEG Correlates of Sustained Attention in a Cohort of Nurses

open access: yesFrontiers in Human Neuroscience, 2018
Mindfulness based training (MBT) is becoming increasingly popular as a means to improve general wellbeing through developing enhanced control over metacognitive processes.
Kian F. Wong   +4 more
doaj   +1 more source

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