Results 61 to 70 of about 2,811,639 (287)

Cognitive Enhancement in Germany

open access: yes, 2016
Sattler S. Cognitive Enhancement in Germany : Prevalence, Attitudes, Moral Acceptability, Terms, Legal Status, and the Ethics Debate. In: Jotterand F, Dubljevic V, eds. Cognitive Enhancement. Ethical and Policy Implications in International Perspectives.
Dubljevic, Veljko   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Cognitive Enhancement in Epilepsy

open access: yes, 2017
Cognitive deficits, including attention, language, and memory dysfunction, are common in the setting of epilepsy and can greatly impair quality of life.
Beth A. Leeman-Markowski   +1 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Selection and perceived impact of walk-up songs in college baseball

open access: yesFrontiers in Psychology
IntroductionMusic and song have the ability to positively affect athletic performance. Music has been demonstrated to increase physical capabilities and improve cognitive function among both recreational and competitive athletes.
Sarah Stokowski   +7 more
doaj   +1 more source

Cognitive Enhancement, Hyperagency, and Responsibility Explosion. [PDF]

open access: yesJ Med Philos
Hyperagency objections appeal to the risk that cognitive enhancement may negatively impact our well-being by giving us too much control. I charitably formulate and engage with a prominent version of this objection due to Sandel (2009)—viz., that ...
Gordon EC.
europepmc   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Is Caffeine a Cognitive Enhancer?

open access: yesJournal of Alzheimer's Disease, 2010
The effects of caffeine on cognition were reviewed based on the large body of literature available on the topic. Caffeine does not usually affect performance in learning and memory tasks, although caffeine may occasionally have facilitatory or inhibitory effects on memory and learning.
openaire   +2 more sources

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