Results 21 to 30 of about 12,104 (269)

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models [PDF]

open access: yesCell Reports, 2020
Summary: NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders.
Jesse E. Hanson   +25 more
doaj   +2 more sources

Therapeutic dilemmas: cognitive enhancers and risk of falling in older adults-a clinical review. [PDF]

open access: yesEur Geriatr Med, 2023
AimTo summarize the falls-related risks of cognitive enhancing medications used to treat neurodegenerative conditions. To assist the clinician in considering the appropriateness of prescribing a cognitive enhancer in an older person at risk of falls and ...
Portlock GE   +4 more
europepmc   +2 more sources

Discovery of Inhibitors of Insulin-Regulated Aminopeptidase as Cognitive Enhancers [PDF]

open access: yesInternational Journal of Hypertension, 2012
The hexapeptide angiotensin IV (Ang IV) is a metabolite of angiotensin II (Ang II) and plays a central role in the brain. It was reported more than two decades ago that intracerebroventricular injection of Ang IV improved memory and learning in the rat ...
Hanna Andersson, Mathias Hallberg
doaj   +2 more sources

Efficacy of different types of cognitive enhancers for patients with schizophrenia: a meta-analysis. [PDF]

open access: yesNPJ Schizophr, 2018
Cognitive impairment is a core feature of schizophrenia, which is predictive for functional outcomes and is, therefore, a treatment target in itself. Yet, literature on efficacy of different pharmaco-therapeutic options is inconsistent. This quantitative
Sinkeviciute I   +11 more
europepmc   +4 more sources

Cognitive enhancers - what we should know about them [PDF]

open access: yesFarmacja Polska, 2021
Nootropics also called smart drugs, memory enhancers, neuroenhancers, cognitive enhancers, are a chemically and pharmacologically heterogeneous group of medicines and active sub-stances that improve mental functions such as memory, intelligence ...
Andrzej Stańczak, Wiesaława Lewgowd
doaj   +1 more source

Psychostimulants as cognitive enhancers – the evidence for the use and abuse of smart drugs

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2022
While modafinil is licensed to treat narcolepsy as a psychostimulant, there is widespread use as a “smart drug” in the young to help study and interest in older populations as a cognitive enhancer.
Poppy Goldsmith, Kirstie Anderson
doaj   +1 more source

The Downsides of Cognitive Enhancement [PDF]

open access: yesThe Neuroscientist, 2020
Cognitive enhancement is becoming progressively popular as a subject of scientific investigation and by the public, although possible adverse effects are not sufficiently understood. We call for cognitive enhancement to build on more specific, mechanistic theories given that a-theoretical approaches to cognitive enhancement are both a cause and a ...
Colzato, Lorenza S.   +2 more
openaire   +3 more sources

The Internet as Cognitive Enhancement [PDF]

open access: yesScience and Engineering Ethics, 2020
Abstract The Internet has been identified in human enhancement scholarship as a powerful cognitive enhancement technology. It offers instant access to almost any type of information, along with the ability to share that information with others. The aim of this paper is to critically assess the enhancement potential of the Internet.
Cristina Voinea   +3 more
openaire   +3 more sources

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