Results 131 to 140 of about 1,611,560 (307)
Introduction: MS is an autoimmune and destructive disease of the central nervous system with different disease progressions that lead to physical and cognitive disabilities.
Parisa Motamedi +4 more
doaj +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
ERP analysis of cognitive sequencing : a left-anterior negativity related to structural transformation processing [PDF]
A major objective of cognitive neuroscience is to identify those neurocomputational processes that may be shared by multiple cognitive functions vs those that are highly specifc.
Dominey, Peter-Ford, Hoen, Michel
core
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
The Comparison of the Executive-Neurological Functions of the Narcotic Addicted and Normal Adults
Aim: The purpose of present research was the comparison of executive-neurological functions of narcotics addicted and normal adults. Method: In this causal-comparative study 38 narcotics addicted person selected of two addiction treatment clinics in ...
Fereshteh Amini +2 more
doaj
Background Given the increasing prevalence of Mild Cognitive Impairment (MCI) among the elderly as a precursor to dementia, understanding how targeted interventions can improve daily functioning and delay cognitive decline is critical to improving ...
Kevser Gursan, Kılıchan Bayar
doaj +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Editorial: Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases
Elodie Ey +5 more
doaj +1 more source

