Results 181 to 190 of about 602,786 (295)

Transient demyelination causes long‐term cognitive impairment, myelin alteration and network synchrony defects [PDF]

Océane Mercier, Pascale Quilichini, Karine Magalon, Florian Gil, Antoine Ghestem, Fabrice Richard, Thomas Boudier, Myriam Cayre, Pascale Durbec   +8 more
openalex   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Development of a core outcome set for clinical trials of interventions to improve sleep in people with cognitive impairment-the Sleep in Cognitive Impairment Core Outcome Set (SCICOS). [PDF]

Alzheimers Dement
Crowley P, Henry AL, Flanagan E, Antonsdottir I, Bentley A, Blackman J, Bliwise DL, Bubu OM, Buysse DJ, Camargos EF, Cassidy-Eagle E, Cote K, Coulthard E, D'Rozario AL, Espie CA, Falck RS, Gabb VG, Harvey AG, Hmwe NTT, Hoyos CM, Jobbins L, Kennelly S, Kent BA, Köpke S, Krystal A, Leroi I, Liguori C, Lim YY, Lorenz R, Lucey BP, Mander B, Moline M, Naismith SL, Ogunniyi A, Rapaport P, Reynolds CF, Richards K, Siengsukon CF, Sindi S, Singer CM, Wirz-Justice A, Yaffe K, O'Caoimh R.   +42 more
europepmc   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

A case report of CLIPPERS syndrome with gait and cognitive impairment. [PDF]

BMC Neurol
Shrestha AM, Bashyal S, Kharbuja N, Subedi RC, Paudel R.   +4 more
europepmc   +1 more source

Health care professionals' perspectives on medication safety among older migrants with cognitive impairment exposed to polypharmacy – A qualitative explorative study

, 2022
Camilla Lynnerup, Charlotte Rossing, Morten Sodemann, Jesper Ryg, Anton Pottegård, Dorthe Susanne Nielsen   +5 more
openalex   +1 more source

Redox‐Active Polyphenol Red Molecularly Imprinted Polymers on Porous Gold Electrodes for Ultrasensitive, AI‐Assisted Detection of Alzheimer's Biomarkers in Undiluted Biofluids

Advanced Healthcare Materials, EarlyView.
This work presents a low‐cost, reagent‐free point‐of‐care biosensor integrating redox‐active polyphenol red molecularly imprinted polymers (pPhR MIPs) on highly porous gold (HPG) electrodes for ultrasensitive detection of phosphorylated tau 181 (p‐Tau 181), an Alzheimer’s disease biomarker, in undiluted biofluids.
Sudhaunsh Deshpande, Ajith Mohan Arjun, Guoyi Liu, Kryztof Pawlak, Sanjiv Sharma   +4 more
wiley   +1 more source

Development and validation of a nomogram for identifying cognitive impairment in patients with leukoaraiosis. [PDF]

BMC Neurol
Zhang G, Meng L, Xu M, Huang C, Lu Y, Yin L, Li J, Xu W.   +7 more
europepmc   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Therapeutic strategies in vascular cognitive impairment: A systematic review and meta-analysis. [PDF]

Alzheimers Dement
Masserini F, Gendarini C, Baso G, Salvadori E, Pantoni L.   +4 more
europepmc   +1 more source