Results 221 to 230 of about 641,525 (312)
Environmental noise in geriatric long-term care: Assessment of techniques targeting the reduction of behavior problems in cognitively impaired individuals [PDF]
C. J. De Bruyn Kops+5 more
openalex +1 more source
Genetics‐Based Targeting Strategies for Precise Neuromodulation
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He+11 more
wiley +1 more source
A sexual consent and education assessment for the cognitively impaired [PDF]
C.H. Kennedy
openalex +1 more source
Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin+9 more
wiley +1 more source
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim+19 more
wiley +1 more source
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin+7 more
wiley +1 more source
Regional metabolic patterns in mild cognitive impairment and Alzheimer’s disease [PDF]
Kejal Kantarci+10 more
openalex +1 more source