Results 211 to 220 of about 4,454,503 (388)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Association of psychosis with cognitive impairment is mediated by amyloidopathy in cognitive impairment. [PDF]

Front Aging Neurosci
Pyun JM, Han S, Park SW, Yeo NY, Park YH, Kim SY, Youn YC, Jang JW, and the Alzheimer’s Disease Neuroimaging Initiative.   +8 more
europepmc   +1 more source

CSF Aβ42 and tau in Parkinson's disease with cognitive impairment

Movement Disorders, 2010
J. Schicks, M. Synofzik, Claudia Schulte, Ludger Schöls   +3 more
semanticscholar   +1 more source

VALUTAZIONE DELLA FUNZIONE AUTONOMICA NEL MILD COGNITIVE IMPAIRMENT TRAMITE ANALISI SPETTRALE DELLA HEART RATE VARIABILITY

, 2013
Paola Nicolini
openalex   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Plasma miRNAs associated with cognitive impairment and brain hypometabolism in individuals with mild cognitive impairment. [PDF]

BMC Neurol
Faeed M, Hosseini H, Abdollahi A, Aziz M, Darabi H, Sohrabi-Ashlaghi A, Farhadi S, Nobari MN, Badakhshan H.   +8 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Age-dependent white matter inflammation and cognitive impairment in the TgAPP21 rat model of Alzheimer disease [PDF]

, 2018
M Brodsky, S Anderson, C Murchison, T Chen, Z Mirzadeh, F Ponce, T Aziz, M Hariz, T Chen, Z Mirzadeh, K Chapple, M Brodsky, S Anderson, C Murchison, C Carroll, R Scott, L Davies, T Aziz, A Fytagoridis, M strm, J Samuelsson, P Blomstedt, M Brodsky, S Anderson, C Murchison, E Mulroy, N Robertson, L Macdonald, A Bok, M Simpson, T Wachter, A Minguez-Castellanos, F Valldeoriola, J Herzog, H Stoevelaar, Z Mirzadeh, K Chapple, M Lambert, A Trster, A Levit, B Allman, R Nagalingam, V Hachinski, S Whitehead   +43 more
openalex   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Mild cognitive impairment and subjective cognitive impairment [PDF]

Psychogeriatrics, 2008
Masatoshi TAKEDA, Takashi MORIHARA, Masayasu OKOCHI, Golam SADIK, Toshihisa TANAKA   +4 more
openaire   +1 more source