Results 61 to 70 of about 192,229 (256)
Spatial Representations in the Human Brain
Frontiers in Human Neuroscience, 2018 While extensive research on the neurophysiology of spatial memory has been carried out in rodents, memory research in humans had traditionally focused on more abstract, language-based tasks.
Nora A. Herweg, Michael J. Kahana
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Cogent Economics & Finance, 2014 This research aims to achieve a better understanding of the modes of conceptualization and thinking on issues of governance. It is part of a cognitive approach, to our knowledge unprecedented.
Garoui Nassreddine, Jarboui Anis
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
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How different travel media promote tourism activities
Journal of Asian Architecture and Building Engineering, 2019 This study was conducted in the city of Yokohama, which has featured several charming tourist attractions such as Chinatown and old Western-style historical buildings, as the place of study to investigate the difference between tourists using paper maps ...
Hung-Yu Chen +2 more
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Frontiers in Neural CircuitsAs an evolutionarily ancient sense, olfaction is key to learning where to find food, shelter, mates, and important landmarks in an animal’s environment. Brain circuitry linking odor and navigation appears to be a well conserved multi-region system among ...
Olivia McKissick +3 more
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Geospatial images in the acquisition of spatial knowledge for wayfinding
Journal of Spatial Information Science, 2012 Geospatial images, such as maps and aerial photographs, are important sources of spatial knowledge that people use for wayfinding. The rapid development of geodata acquisition and digital graphics has recently led to rather complete geographic coverage ...
Pyry Kettunen +4 more
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