Results 71 to 80 of about 192,229 (256)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The Map’s Design: Evolution’s Impact on Navigation and Spatial Cognition
AnimalsSpatial cognition is fundamental to an animal’s ability to move through and interact with its environment. Thus, understanding the physiological basis for this cognitive function and how it varies across taxa is fundamental to understanding how ecology ...
Isabella S. Olynik-McLaughlin +1 more
doaj +1 more source
Semantic elaboration in auditory and visual spatial memory
Frontiers in Psychology, 2010 The aim of this study was to investigate the hypothesis that semantic information facilitates auditory and visual spatial learning and memory. An auditory spatial task was administered, whereby healthy participants were placed in the center of a semi ...
Meghan eTaevs +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Cognitive modeling: theoretical bases, methods, limitations
Russian Journal of Economics and LawObjective: to review the field of cognitive-intelligent modeling and the field of knowledge visualization to identify unresolved issues, challenges and risks.Methods: an overview of the field of cognitive modeling, which is viewed as a set of methods for
S. G. Zbrishchak
doaj +1 more source
Head direction maps remain stable despite grid map fragmentation
Frontiers in Neural Circuits, 2012 Areas encoding space in the brain contain both representations of position (place cells and grid cells) and representations of azimuth (head direction cells).
Jonathan R Whitlock, Dori eDerdikman
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
MATEC Web of Conferences, 2018 Under the background of the rise of the national theme park, the design connotation of the theme park, the scientific planning of landscape design and the design of the surrounding environment make the theme park more suitable for the aesthetics of ...
Zang Han, An Yong-gang, Pang Xiaolin
doaj +1 more source
Italian Journal of Agronomy, 2010 A methodological framework was designed to assess the effectiveness of agri-environmental policy measures adopted by the Veneto Region to reduce diffuse water pollution of agricultural origin.
Marta Carpani, Carlo Giupponi
doaj +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source