Results 161 to 170 of about 9,813 (270)

Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION The brain is a complex dynamical system, influenced by arousal state. Cortical synchrony supports information processing and is disrupted in Alzheimer's disease (AD). Locus coeruleus (LC) integrity and pupillometry index arousal system structure and function.
Michael C. B. David, Emma‐Jane Mallas, Magdalena A. Kolanko, Martina Del Giovane, Danielle L. Kurtin, Ramin Nilforooshan, Karl A. Zimmerman, Cristina Bonet Olivares, Peter J. Lally, CR&T Group of UKDRI, David J. Sharp, Paresh A. Malhotra, Gregory Scott   +12 more
wiley   +1 more source

Functional Segregation of Epileptogenicity within the Human Amygdala

Annals of Neurology, Volume 99, Issue 6, Page 1598-1612, June 2026.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys, Julia Makhalova, Samuel Medina Villalon, Maria Fratello, Hugo Dary, Stanislas Lagarde, Francesca Pizzo, Agnès Trébuchon, Maxime Guye, Jean‐Philippe Ranjeva, Romain Carron, Didier Scavarda, Christian‐George Bénar, Bernard Giusiano, Fabrice Bartolomei   +14 more
wiley   +1 more source

Clinical Spectrum, Heteroplasmy‐Phenotype Correlation, and Prognosis of the MT‐ND3 m.10191 T > C Mutation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study presents the largest cohort of patients with the m.10191 T > C mutation to date, delineating a continuous spectrum from LS to MELAS‐like phenotypes and systematically characterizing clinical manifestations, neuroimaging features, heteroplasmy–phenotype correlations, and prognostic factors.
Zimeng He, Huafang Jiang, Tongyue Li, Yang Liu, Ying Zou, Chaolong Xu, Zhimei Liu, Danmin Shen, Ruoyu Duan, Minhan Song, Yunxi Zhang, Zixuan Zhang, Mingxi Sun, Rui Shen, Hong Xue, Fang Fang   +15 more
wiley   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Defining the end point of status epilepticus: A scoping review and framework for standardization

Epilepsia, Volume 67, Issue 6, Page 2673-2688, June 2026.
Abstract Status epilepticus (SE) is a life‐threatening neurological emergency with consensus‐driven definitions for onset but no standardized criteria for its end point. This gap creates uncertainty in research and clinical practice. We conducted a scoping review to evaluate how end points have been defined in SE research and to identify key areas of ...
Fawad A. Khan, Margaret T. Gopaul, Samuel L. Carter, Anil Chimakurthy, Summer Skelton, Lawrence J. Hirsch, Eugen Trinka   +6 more
wiley   +1 more source

Advances in Sensor-Based Technologies for Health, Aging, and Intelligent Care. [PDF]

Sensors (Basel)
Liu L, Miguel Cruz A.
europepmc   +1 more source

Potential of Aeginetia indica for Alzheimer's Disease Management: In Vitro, In Vivo, and Computational Insights

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
MeOH extract of Aeginetia indica (AİME); chromatographic study: LCMS/MS and GCMS; in vitro assays: AChE assays → ↓ AChE level, ↓ inflammation level and antioxidant assays → ROS; in vivo anti‐inflammatory study: ↓ inflammation level; molecular docking → molecular dynamics simulations: acacetin and acteoside.
Marjanur Rahman Bhuiyan, Md. Sharif Reza, Sadikur Rahman Shuvo, Mustafa Abdullah Yilmaz, Syed Mumtahin Mannan Siam, Md. Shadman Sakib, Oguz Cakir, Md. Nazmul Islam Durjoy, Abbas Tarhan, Nuraniye Eruygur, A. F. M. Shahid Ud Daula   +10 more
wiley   +1 more source

Radar-Based Assessment of Sit-to-Stand Transitions as Digital Biomarkers of Pain and Physical Decline. [PDF]

Sensors (Basel)
Ziaee Bideskan M, Karbaschi N, Abedi H, Abbasi Z.   +3 more
europepmc   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, Volume 2, Issue 2, June 2026.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

Remote monitoring of instrumental activities of daily living reveals intrinsic capacity in older adults. [PDF]

Gerontology
Lee M, Gidh N, Azarian M, Beom J, York MK, Kunik ME, Vaziri A, Najafi B.   +7 more
europepmc   +1 more source