Results 91 to 100 of about 49,434 (284)

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Study on the relationship between cognitive reserve and cognitive impairment in patients with traumatic brain injury

Huli yanjiu
ObjectiveTo explore the relationship between cognitive reserve and the risk of cognitive impairment after traumatic brain injury.MethodsFrom September 2023 to August 20,2024,patients with TBI who were hospitalized in the department of neurosurgery or ...
LUO Sixiong, XU Yi, ZHU Xiaoju, ZHANG Guanghui, FENG Xianhong, WANG Zonghua   +5 more
doaj  

The role of cognitive reserve in white matter hyperintensities: from cognitive aging to Alzheimer's spectrum

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION White matter hyperintensities (WMHs) are characteristic of Alzheimer's disease (AD), and cognitive reserve (CR) protects cognitive function. However, whether WMHs mediate the CR–cognition relationship remains unclear.
Yu‐Ruei Lin, Wei‐Lu Lee, Jong‐Ling Fuh   +2 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Association of Lifespan Cognitive Reserve and Cognitive Trajectories Considered Apoe Ε4

, 2023
Huilian Duan, Zhenshu Li, Cheng Cheng, Ning Xu, Tong Yang, Qi Wu, Zehao Wang, Fei Ma, Yongjie Chen, Yue Du, Meilin Zhang, Jing Yan, Changqing Sun, Guangshun Wang, Wen Li, Guowei Huang   +15 more
openalex   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

The role of cerebral-cognitive reserve in the birth of a child with Alzheimer’s in late-life individuals

European Psychiatry
Introduction The modern understanding of AD allows us to consider it through the constructs of “vulnerability” and “stability” of the brain in relation to the pathological effects of neurodegeneration.
A. Sidenkova
doaj   +1 more source

Cognitive reserve to modify the trajectory of dementia: what does it represent for Oaxaca, Mexico? [PDF]

, 2023
Gemma M. Martínez-Martínez, Douglas C. Nance, Elizabeth Muñoz Ortiz   +2 more
openalex   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source