Results 211 to 220 of about 227,180 (304)

Quantifying motor-cognitive reserve using a novel multi-modal stress test. [PDF]

Brain Commun
Kozlovski T, Maidan I, Gazit E, Droby A, Thaler A, Hausdorff JM, Giladi N, Benjamini Y, Mirelman A.   +8 more
europepmc   +1 more source

Cognitive reserve: an evolving concept

International Psychogeriatrics, 2020
openaire   +2 more sources

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Regional patch-based MRI brain age modeling with an interpretable cognitive reserve proxy. [PDF]

Pattern Recognit Lett
Maddox S, Puglisi L, Darabifard F, Australian Imaging Biomarkers and Lifestyle flagship study of aging, Sami S, Ravi D.   +5 more
europepmc   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Perceived control, brain health, and cognitive reserve: longitudinal resilience mechanisms in Black, White, and Hispanic older adults. [PDF]

J Gerontol B Psychol Sci Soc Sci
Walters ME, Scambray KA, Morris EP, Palms JD, Pierce RM, Sol K, Schupf N, Brickman AM, Zahodne LB.   +8 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source