Results 31 to 40 of about 643,418 (263)

The morphodynamical turn of cognitive linguistics

open access: yesSignata, 2011
The paper summarizes the history of the morphodynamical turn in cognitive semio-linguistics. From the earliest Thom’s models introduced in the late 1960s to the recent Cognitive Morphodynamics (2011), it deals with forty years of research covering (i ...
Jean Petitot
doaj   +1 more source

Retour sur la question du naturalisme en sciences sociales

open access: yesSociologies, 2022
Generally speaking, the term naturalism provokes suspicion among social scientists. However, as Dan Sperber reminds us (Sperber, Coubray, & Schmitt, 2011), the naturalistic ambition originally covered a monistic (thus opposed to dualism) and ...
Jean-Sébastien Vayre
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Review of 'Eternalized Fragments: Reclaiming Aesthetics in Contemporary World Fiction' (2020) by W. Michelle Wang

open access: yesThe Parish Review, 2021
Flore E. Coulouma, ‘Review of Eternalized Fragments: Reclaiming Aesthetics in Contemporary World Fiction (2020) by W. Michelle Wang,’ The Parish Review: Journal of Flann O’Brien Studies 4, no. 2 (Spring 2020): 1–6. Available at: https://
Flore E. COULOUMA
doaj   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Stereoscopic vision in Wilfrid Sellars’ thought: ontological approaches through post-contemporary art

open access: yesArtnodes, 2023
By analyzing Wilfrid Sellars’s contributions to dealing with the complexity of what knowledge is and how it is formed – epistemology and ontology – and Thomas Metzinger’s theoretical complement to Sellars’ ontology, I explore how the impasse in ...
Miguel Ángel Rego Robles
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

РАЗВИТИЕ КОГНИТОЛОГИИ КАК НАУЧНОГО НАПРАВЛЕНИЯ И ИСПОЛЬЗОВАНИЕ ЕГО ПРИ РЕШЕНИИ СОЦИАЛЬНО-ЭКОНОМИЧЕСКИХ ЗАДАЧ

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2014
В статье рассматриваются предпосылки возникновения когнитологии как научного направления и история его развития. Анализируется сущность когнитивного подхода и особенности его применения при решении социально-экономических проблем.
В. Е. Хаустова   +1 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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