Results 61 to 70 of about 2,208,651 (236)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Thinking Styles And Its Relationship With The Need for Cognitive for Students of University

مجلة كلية التربية للبنات, 2019
This study aims to recognize the most common thinking styles and level of the need for cognitive university students , the relation between thinking styles and the need for cognitive, and there are differences according to gender .The sample consists of (
ازهار هادي العتابي
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Personalizing the design of computer‐based instruction to enhance learning [PDF]

, 1998
This paper reports two studies designed to investigate the effect on learning outcomes of matching individuals’ preferred cognitive styles to computer‐based instructional (CBI) material.
Hitendra Pillay, Boles, Wageeh W., Leonard Raj, Pillay, Hitendra, Boles, Wageeh, Wageeh Boles, Raj, Leonard, Pillay, Hitendra K.   +7 more
core   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Modeling users’ web search behavior and their cognitive styles [PDF]

, 2014
Previous studies have shown that users' cognitive styles play an important role during web searching. However, only a limited number of studies have showed the relationship between cognitive styles and web search behavior.
Partridge, Helen L., Kinley, Khamsum, Edwards, Sylvia L., Tjondronegoro, Dian, Edwards, Sylvia, Partridge, Helen, Tjondronegoro, Dian W.   +6 more
core   +2 more sources

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Catering for different learning styles [PDF]

, 1995
This paper describes a study to investigate the possibility of applying a quick and simple front‐end to multimedia presentations. The front‐end will determine the user's learning style and suggest a suitable navigation method The paper recognizes not ...
Jones, Clifford, Manfred Kwok, Kwok, Manfred, Clifford Jones   +3 more
core   +1 more source

Are we on the same wavelength? Supervisor-subordinate cognitive style congruence and its association with supervisors’ self-awareness through leader member exchange

Frontiers in Psychology
IntroductionLeaders’ self-awareness is essential to leadership effectiveness. Cognitive styles—how individuals perceive and process information—are key factors in fostering self-awareness.
Faisal AlReshaid, Alper Erturk, Razan Alkhayyat, Farid Abdallah, Oualid Abidi, Marcelle De La Roche   +5 more
doaj   +1 more source