Results 31 to 40 of about 580,232 (316)

Cardiovascular risk moderates the effect of aerobic exercise on executive functions in older adults with subcortical ischemic vascular cognitive impairment

open access: yesScientific Reports, 2021
Aerobic training (AT) can promote cognitive function in adults with Subcortical Ischemic Vascular Cognitive Impairment (SIVCI) by modifying cardiovascular risk factors.
Cindy K. Barha   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Prenatal psychosocial factors and changes in marital satisfaction after childbirth: an online cohort study of pregnant women

open access: yesBMC Pregnancy and Childbirth
Background Marital satisfaction is a key determinant of maternal mental health during the perinatal period. Identifying psychosocial factors associated with changes in marital satisfaction can help inform early preventive interventions.
Chika Kubota   +13 more
doaj   +1 more source

What does neuroscience offer us in understanding cognitive therapy and person-centred therapy for depression? A realist synthesis review [PDF]

open access: yes, 2011
A need for increased access to effective therapies for depression has been identified in the United Kingdom. There has been significant investment in Cognitive Therapy but a perceived lack of funding for alternatives.
Ruby, Madi A.
core  

Coping styles predict responsiveness to cognitive behaviour therapy in psychosis

open access: yes, 2011
The study aimed to determine the clinical and neuropsychological predictors of responsiveness to cognitive behavioural therapy for psychosis (CBTp). Sixty patients with schizophrenia or schizoaffective disorder and 25 healthy individuals took part in the
Peters, Emmanuelle R.   +19 more
core   +1 more source

Does emotional reasoning change during cognitive behavioural therapy for anxiety? [PDF]

open access: yes, 2016
© 2015 Swedish Association for Behaviour Therapy. Abstract: Emotional reasoning refers to the use of subjective emotions, rather than objective evidence, to form conclusions about oneself and the world. It is a key interpretative bias in cognitive models
Moulds, ML   +15 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Systemic therapy informed self-help and paraprofessional training in a naturalistic setting: study protocol of a digital randomised trial

open access: yesArchives of Public Health
Background Multiple studies have shown the efficacy of Systemic Psychotherapy (ST) approaches as a promising path to address various mental health disorders and alleviate psychological distress.
Pieter Erasmus   +6 more
doaj   +1 more source

Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review

open access: yesBMC Geriatrics, 2017
Background Worldwide, the population is aging and the number of individuals diagnosed with dementia is rising rapidly. Currently, there are no effective pharmaceutical cures.
Lisanne F. ten Brinke   +3 more
doaj   +1 more source

Daily blood pressure profile and blood–brain barrier permeability in patients with cerebral small vessel disease

open access: yesScientific Reports, 2022
Cerebral small vessel disease (CSVD) plays an important role in cognitive impairment, stroke, disability, and death. Hypertension is the main risk factor for CSVD.
L. A. Dobrynina   +6 more
doaj   +1 more source

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